Serum-Free Suspension Culture of the <i>Aedes albopictus</i> C6/36 Cell Line for Chimeric Orthoflavivirus Vaccine Production

Serum-Free Suspension Culture of the <i>Aedes albopictus</i> C6/36 Cell Line for Chimeric Orthoflavivirus Vaccine Production

Chimeric orthoflaviviruses derived from the insect-specific Binjari virus (BinJV) offer a promising basis for safe orthoflavivirus vaccines. However, these vaccines have so far only been produced using adherent C6/36 <i>Aedes albopictus</i> mosquito cell cultures grown in serum-supplemen...

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Bibliographic Details
Main Authors: Joshua S. Dawurung, Jessica J. Harrison, Naphak Modhiran, Roy A. Hall, Jody Hobson-Peters, Henry de Malmanche
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Viruses
Subjects:
suspension culture
C6/36
vaccines
orthoflavivirus chimaeras
virus bioprocessing
Online Access:https://www.mdpi.com/1999-4915/17/2/250
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