Does Extended Serum Sample Storage Impact Laboratory Results?
Background: Prolonged storage of samples can result in changes to routine biochemical parameters. Aim: This study aimed to examine the biochemical changes in serum samples stored at –20°C for extended periods (72 hours), focusing on various routine biochemical parameters. Results: Significant...
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Gujarat Adani Institute of Medical Sciences
2025-01-01
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| Series: | GAIMS Journal of Medical Sciences |
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| Online Access: | https://gjms.gaims.ac.in/index.php/gjms/article/view/365/194 |
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| author | Balaji Pillai Ajeet Kumar Khilnani Dinesh Sharma |
| author_facet | Balaji Pillai Ajeet Kumar Khilnani Dinesh Sharma |
| author_sort | Balaji Pillai |
| collection | DOAJ |
| description | Background: Prolonged storage of samples can result in changes to routine biochemical parameters.
Aim: This study aimed to examine the biochemical changes in serum samples stored at –20°C for extended periods (72 hours), focusing on various routine biochemical parameters.
Results: Significant changes were noted in serum glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, and potassium levels after 72 hours of storage, with further deterioration observed over 3 months. The remaining parameters showed no significant alterations.
Conclusion: Prolonged sample storage results in changes in analyte concentrations in serum. Serum glucose, AST, ALT, creatinine, and potassium levels should be measured within 72 hours if extended storage is necessary. All parameters should ideally be analyzed within 24 hours to prevent misinterpretation of results and ensure optimal patient care. |
| format | Article |
| id | doaj-art-4c2c4dae97184f7f8d17044a05613d4d |
| institution | Kabale University |
| issn | 2583-1763 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Gujarat Adani Institute of Medical Sciences |
| record_format | Article |
| series | GAIMS Journal of Medical Sciences |
| spelling | doaj-art-4c2c4dae97184f7f8d17044a05613d4d2025-01-22T10:01:18ZengGujarat Adani Institute of Medical SciencesGAIMS Journal of Medical Sciences2583-17632025-01-0151161166https://doi.org/10.5281/zenodo.14716328Does Extended Serum Sample Storage Impact Laboratory Results?Balaji Pillai0Ajeet Kumar Khilnani1https://orcid.org/0000-0003-3592-6340Dinesh Sharma2Departments of Otorhinolaryngology, Gujarat Adani Institute of Medical Sciences, Bhuj, Kachchh, GujaratDepartments of Otorhinolaryngology, Gujarat Adani Institute of Medical Sciences, Bhuj, Kachchh, GujaratDepartments of Biochemistry, Gujarat Adani Institute of Medical Sciences, Bhuj, Kachchh, GujaratBackground: Prolonged storage of samples can result in changes to routine biochemical parameters. Aim: This study aimed to examine the biochemical changes in serum samples stored at –20°C for extended periods (72 hours), focusing on various routine biochemical parameters. Results: Significant changes were noted in serum glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, and potassium levels after 72 hours of storage, with further deterioration observed over 3 months. The remaining parameters showed no significant alterations. Conclusion: Prolonged sample storage results in changes in analyte concentrations in serum. Serum glucose, AST, ALT, creatinine, and potassium levels should be measured within 72 hours if extended storage is necessary. All parameters should ideally be analyzed within 24 hours to prevent misinterpretation of results and ensure optimal patient care.https://gjms.gaims.ac.in/index.php/gjms/article/view/365/194astaltcreatininebiochemical parameters |
| spellingShingle | Balaji Pillai Ajeet Kumar Khilnani Dinesh Sharma Does Extended Serum Sample Storage Impact Laboratory Results? GAIMS Journal of Medical Sciences ast alt creatinine biochemical parameters |
| title | Does Extended Serum Sample Storage Impact Laboratory Results? |
| title_full | Does Extended Serum Sample Storage Impact Laboratory Results? |
| title_fullStr | Does Extended Serum Sample Storage Impact Laboratory Results? |
| title_full_unstemmed | Does Extended Serum Sample Storage Impact Laboratory Results? |
| title_short | Does Extended Serum Sample Storage Impact Laboratory Results? |
| title_sort | does extended serum sample storage impact laboratory results |
| topic | ast alt creatinine biochemical parameters |
| url | https://gjms.gaims.ac.in/index.php/gjms/article/view/365/194 |
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