Effect and Mechanism of TFAM on Chemotherapy Resistance in Ovarian Cancer Cells Through Metabolic Reprogramming Regulation

Effect and Mechanism of TFAM on Chemotherapy Resistance in Ovarian Cancer Cells Through Metabolic Reprogramming Regulation

ObjectiveTo investigate the role of mitochondrial transcription factor A (TFAM) in platinum-resistant ovarian cancer cells and its effects on metabolic reprogramming and sensitivity to platinum-based drugs MethodsThe mitochondrial function and metabolic characteristics of platinum-resistant ovarian...

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Bibliographic Details
Main Authors: Lingling FAN, Reziwanguli·WUBULI, Linglan LU, Lili HAN
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
mitochondrial transcription factor a
aerobic glycolysis
oxidative phosphorylation
ovarian cancer
chemotherapy resistance
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1072
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