Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?

Abstract Background Pharyngeal arch anomalies are the second most common form of head and neck congenital defect. The second arch anomalies are the most common, and compromise 95% of cases. Little is known about the 3rd and 4th arch anomalies as they are extremely rare. They most commonly present in...

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Main Authors: A. O. Kotwica, J. Rudd, D. J. Howard
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Journal of Otolaryngology - Head and Neck Surgery
Subjects:
Online Access:https://doi.org/10.1186/s40463-020-00475-w
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author A. O. Kotwica
J. Rudd
D. J. Howard
author_facet A. O. Kotwica
J. Rudd
D. J. Howard
author_sort A. O. Kotwica
collection DOAJ
description Abstract Background Pharyngeal arch anomalies are the second most common form of head and neck congenital defect. The second arch anomalies are the most common, and compromise 95% of cases. Little is known about the 3rd and 4th arch anomalies as they are extremely rare. They most commonly present in childhood with sudden severe left lateral neck infection and abscess formation with considerable tendency to recur, contributing to significant mortality and morbidity in those patients. Case presentation Here we present four cases finally diagnosed as third or fourth pharyngeal arch anomalies, with more than 20 years of follow-up following their definitive surgery. The possibility that they are thymopharyngeal duct remnants is discussed. Conclusion Meticulous open radical surgical excision of all involved paralaryngeal, parapharyngeal and thyroid tissue, with preservation of the superior and recurrent laryngeal nerves, is required for cure of recurrent cases. Graphical abstract
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institution Kabale University
issn 1916-0216
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series Journal of Otolaryngology - Head and Neck Surgery
spelling doaj-art-4c087eb05335485287063d4b982512202025-02-03T10:53:56ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162020-12-014911510.1186/s40463-020-00475-wCase report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?A. O. Kotwica0J. Rudd1D. J. Howard2Rhinology and Laryngology Research Fund FellowGreat Ormond Street HospitalRoyal National Throat, Nose and Ear HospitalAbstract Background Pharyngeal arch anomalies are the second most common form of head and neck congenital defect. The second arch anomalies are the most common, and compromise 95% of cases. Little is known about the 3rd and 4th arch anomalies as they are extremely rare. They most commonly present in childhood with sudden severe left lateral neck infection and abscess formation with considerable tendency to recur, contributing to significant mortality and morbidity in those patients. Case presentation Here we present four cases finally diagnosed as third or fourth pharyngeal arch anomalies, with more than 20 years of follow-up following their definitive surgery. The possibility that they are thymopharyngeal duct remnants is discussed. Conclusion Meticulous open radical surgical excision of all involved paralaryngeal, parapharyngeal and thyroid tissue, with preservation of the superior and recurrent laryngeal nerves, is required for cure of recurrent cases. Graphical abstracthttps://doi.org/10.1186/s40463-020-00475-wBranchial archPharyngeal archNeck abscessThymopharyngeal duct remnant
spellingShingle A. O. Kotwica
J. Rudd
D. J. Howard
Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
Journal of Otolaryngology - Head and Neck Surgery
Branchial arch
Pharyngeal arch
Neck abscess
Thymopharyngeal duct remnant
title Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
title_full Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
title_fullStr Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
title_full_unstemmed Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
title_short Case report series: revisiting third and fourth pharyngeal arch anomalies, − are they thymopharyngeal duct remnants?
title_sort case report series revisiting third and fourth pharyngeal arch anomalies are they thymopharyngeal duct remnants
topic Branchial arch
Pharyngeal arch
Neck abscess
Thymopharyngeal duct remnant
url https://doi.org/10.1186/s40463-020-00475-w
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