Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study

Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study

Abstract Background Human umbilical cord mesenchymal stem cells (hUC-MSCs) have great potential for treating autoimmune diseases for their immunomodulatory and tissue-regenerative abilities; however, their therapeutic role in neuromyelitis optica spectrum disorder (NMOSD) remains uncertain. Methods...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chunran Xue, Haojun Yu, Xuzhong Pei, Xiaoying Yao, Jie Ding, Xiying Wang, Yi Chen, Yangtai Guan
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Series:	Stem Cell Research & Therapy
Subjects:	Aquaporin 4 Astrocyte Mesenchymal stem cells Neuromyelitis optica spectrum disorder Umbilical cord
Online Access:	https://doi.org/10.1186/s13287-025-04187-8
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Breaking New Ground: A Seropositive Neuromyelitis Optica (NMOSD) in Ethiopian Patients: A Case Series
by: Yegzeru Belete, et al.
Published: (2025-01-01)

Acute gastroenteritis and unilateral vision loss leading to a diagnosis of aquaporin-4-IgG seropositive neuromyelitis optica spectrum of disorders in a child: A case of atypical optic neuritis in the era of biomarkers
by: N Narainswami
Published: (2024-05-01)

Neuromyelitis optica spectrum disorder: epidemiology, pathogenesis, diagnosis, treatment, and prognosis
by: J. Čemerkaitė, et al.
Published: (2021-03-01)

Analysis of changes in the chemokine CXC ligand 13 in serum and cerebrospinal fluid of patients with neuromyelitis optica
by: Juan Zhou, et al.
Published: (2025-01-01)

Hemorrhagic Longitudinally Extensive Transverse Myelitis (LETM) as a First Presentation of Neuromyelitis Optica Spectrum Disorder (NMOSD): A Case Report and Literature Review
by: Shima Jahani, et al.
Published: (2025-01-01)

Second Trimester Umbilical Cord Coiling Index and Perinatal Outcomes
by: Yusuf Aytaç Tohma, et al.
Published: (2014-12-01)

Research Progress on Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis
by: GONG Jin, et al.
Published: (2025-01-01)

Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators
by: Michael Hecker, et al.
Published: (2025-01-01)

Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice
by: Weifeng Gu, et al.
Published: (2025-01-01)

A qualitative systematic review of umbilical cord care practices in Nigeria
by: Precious Ebube Anyakorah, et al.
Published: (2025-01-01)

The haemodynamic effects of umbilical cord milking in term infants: a randomised controlled trial
by: Mehmet Tekin, et al.
Published: (2023-07-01)

Differentiation between multiple sclerosis and neuromyelitis optic spectrum disorders with multilevel fMRI features: A machine learning analysis
by: Xiao Liang, et al.
Published: (2025-01-01)

Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13
by: Kun-Chi Wu, et al.
Published: (2025-01-01)

PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response
by: Tian L, et al.
Published: (2025-01-01)

Excessive Weight Gain During Pregnancy Increased Ponoxarase 1 Level in Neonatal Cord Blood
by: Serhat Ege, et al.
Published: (2025-01-01)

Functional abnormalities of the glymphatic system in cognitive disorders
by: Wuyue Shentu, et al.
Published: (2025-12-01)

Development of an analytical method for the simultaneous determination of 22 Polycyclic Aromatic Hydrocarbons (PAHs) in maternal and umbilical cord blood
by: Swiha, Stéphanie, et al.
Published: (2024-02-01)

Umbilical Hernia as Forerunner of Primary Umbilical Endometriosis: A Case Report
by: Saunri Hansadah, et al.
Published: (2021-12-01)

Constructing a potential HLA haplo-homozygous induced pluripotent stem cell haplobank using data from an umbilical cord blood bank
by: Ji He, et al.
Published: (2025-02-01)

Astrocytic heterogeneous nuclear ribonucleoprotein U is involved in scar formation after spinal cord injury
by: Lili Quan, et al.
Published: (2025-01-01)

Quality Control of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles
by: Krishnan I, et al.
Published: (2025-02-01)

Efficacy of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles in Metabolic Syndrome
by: Illayaraja Krishnan, et al.
Published: (2025-01-01)

Surface Roughness Analysis of Subsea Cables/Umbilicals
by: Ahmed Reda, et al.
Published: (2025-01-01)

The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders
by: Veronika Spahlinger, et al.
Published: (2019-01-01)

Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering
by: Ryohei Yamamura, et al.
Published: (2025-02-01)

Umbilical hernia and pregnancy. A case presentation.
by: Julio Sarmiento Sánchez, et al.
Published: (2008-12-01)

Conditioned medium derived from mesenchymal stem cells and spinal cord injury: A review of the current therapeutic capacities
by: Gholam Reza Kaka, et al.
Published: (2025-06-01)

The epidemiology and clinical presentation of seropositive neuromyelitis optica spectrum disorder in a US population
by: Aaron M. Carlson, et al.
Published: (2025-01-01)

Mechanisms of Cancer-Induced Bone Pain
by: Wang X, et al.
Published: (2025-01-01)

Neuromyelitis Optica Spectrum Disease with Positive Autoimmune Indices: A Case Report and Review of the Literature
by: M. E. Evangelopoulos, et al.
Published: (2011-01-01)

Insights into neuromyelitis optica spectrum disorder and pregnancy from a single-center study in Thailand
by: Nuttakarn Budtarad, et al.
Published: (2025-02-01)

Primary Umbilical Endometriosis: Villar's Nodule
by: Christos IAVAZZO, et al.
Published: (2022-03-01)

Levels of IL-6 and IL-1β in Umbilical Cord Blood in Relation to Mode of Birth
by: Ebru Aslan Patlakoğlu, et al.
Published: (2014-04-01)

Evolution of the umbilical cord blood proteome across gestational development
by: Leena B. Mithal, et al.
Published: (2025-01-01)

Acute Respiratory Failure due to Neuromyelitis Optica Treated Successfully with Plasmapheresis
by: Massa Zantah, et al.
Published: (2016-01-01)

Determination of remifentanil in neonatal dried blood spots by liquid chromatography-tandem mass spectrometry
by: Trontelj Jurij, et al.
Published: (2024-06-01)

Soliton Management for Ultra-high Speed Telecommunications
by: Vladimir N. Serkin, et al.
Published: (2001-01-01)

Evaluation of Clinical Interest of Anti-Aquaporin-4 Autoantibody Followup in Neuromyelitis Optica
by: Jean-Baptiste Chanson, et al.
Published: (2013-01-01)

Umbilical Artery Doppler Findings in Patients with Preterm Premature Rupture of Membranes
by: Oya Aldemir, et al.
Published: (2014-12-01)

Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Skin Matrix Synthesis and Pigmentation
by: Kee LT, et al.
Published: (2025-02-01)