A novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease.

A novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease.

Influenza A virus seasonal outbreaks and occasional pandemics represent a global health threat. The high genetic instability of this virus permits rapid escape from the host immune system and emergence of resistance to antivirals. There is thus an urgent need to develop novel approaches for efficien...

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Bibliographic Details
Main Authors: Julie Motard, Ronan Rouxel, Alexandra Paun, Veronika von Messling, Martin Bisaillon, Jean-Pierre Perreault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0027327&type=printable
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