Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma.

Peroxidasin (PXDN), is a heme peroxidase with a critical role in the crosslinking of type IV collagen, being essential for basement membrane integrity. Overexpression of PXDN has been associated with poor clinical outcomes in many cancers; however, little is currently known about its role in renal c...

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Main Authors: Roberto Silva, Jorge Reis Almeida, Ana Rita Coelho, Isabel Brandão, Bárbara Gomes, Inês Soares Alencastre, João Paulo Oliveira
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Experimental and Molecular Pathology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0014480025000437
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