Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis
Abstract Background The embryological development of the testicles and their descent to the scrotum is multifactorial process, and the role of the internal inguinal ring has not yet been clarified. In this study, we aimed to assess the role of the internal inguinal ring in this process by comparing...
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BMC
2025-06-01
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| Series: | Basic and Clinical Andrology |
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| Online Access: | https://doi.org/10.1186/s12610-025-00270-5 |
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| author | Serkan Yenigurbuz Caner Ediz Hasan Huseyin Tavukcu Serkan Akan Omer Yilmaz |
| author_facet | Serkan Yenigurbuz Caner Ediz Hasan Huseyin Tavukcu Serkan Akan Omer Yilmaz |
| author_sort | Serkan Yenigurbuz |
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| description | Abstract Background The embryological development of the testicles and their descent to the scrotum is multifactorial process, and the role of the internal inguinal ring has not yet been clarified. In this study, we aimed to assess the role of the internal inguinal ring in this process by comparing the inguinal and abdominal orchiectomy specimens histopathologically. The patients were classified according to localization of the undescended testicle as group 1 (n = 11), consisting of abdominal-localized individuals, and group 2 (n = 40), composed of inguinal-localized individuals. Data regarding age, side of the undescended testicle, testicular volume, spermatic cord length, testosterone level, semen analysis, and histopathological reports of undescended testicles in both groups were analyzed and compared. Results The median age of groups 1 and 2 was twenty-one. The median testicular volume was significantly lower in group 1 than in group 2 (p = 0.002). In addition, progressive motility and normal sperm morphology rates were substantially higher in group 2 than in group 1 (p = 0.019 vs p = 0.029). There was no difference between the groups in terms of analyses of histopathological parameters performed in testis tissue. (p > 0.05). Conclusions Although testicular volume, sperm motility, and normal morphology rates were lower in abdominal testes, no significant differences were found in histopathological parameters between the groups. |
| format | Article |
| id | doaj-art-4be4f569e68c4d1fb3e39e3ee698b646 |
| institution | Kabale University |
| issn | 2051-4190 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | BMC |
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| series | Basic and Clinical Andrology |
| spelling | doaj-art-4be4f569e68c4d1fb3e39e3ee698b6462025-08-20T03:47:24ZengBMCBasic and Clinical Andrology2051-41902025-06-013511610.1186/s12610-025-00270-5Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testisSerkan Yenigurbuz0Caner Ediz1Hasan Huseyin Tavukcu2Serkan Akan3Omer Yilmaz4Department of Urology, Sultan Abdulhamid Han Education and Research HospitalDepartment of Urology, Sultan Abdulhamid Han Education and Research HospitalDepartment of Urology, Medipol HospitalDepartment of Urology, Fatih Sultan Mehmet Education and Research HospitalDepartment of Urology, Sultan Abdulhamid Han Education and Research HospitalAbstract Background The embryological development of the testicles and their descent to the scrotum is multifactorial process, and the role of the internal inguinal ring has not yet been clarified. In this study, we aimed to assess the role of the internal inguinal ring in this process by comparing the inguinal and abdominal orchiectomy specimens histopathologically. The patients were classified according to localization of the undescended testicle as group 1 (n = 11), consisting of abdominal-localized individuals, and group 2 (n = 40), composed of inguinal-localized individuals. Data regarding age, side of the undescended testicle, testicular volume, spermatic cord length, testosterone level, semen analysis, and histopathological reports of undescended testicles in both groups were analyzed and compared. Results The median age of groups 1 and 2 was twenty-one. The median testicular volume was significantly lower in group 1 than in group 2 (p = 0.002). In addition, progressive motility and normal sperm morphology rates were substantially higher in group 2 than in group 1 (p = 0.019 vs p = 0.029). There was no difference between the groups in terms of analyses of histopathological parameters performed in testis tissue. (p > 0.05). Conclusions Although testicular volume, sperm motility, and normal morphology rates were lower in abdominal testes, no significant differences were found in histopathological parameters between the groups.https://doi.org/10.1186/s12610-025-00270-5Undescended TestisOrchiectomyFertilityHistologyTesticular cancer |
| spellingShingle | Serkan Yenigurbuz Caner Ediz Hasan Huseyin Tavukcu Serkan Akan Omer Yilmaz Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis Basic and Clinical Andrology Undescended Testis Orchiectomy Fertility Histology Testicular cancer |
| title | Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| title_full | Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| title_fullStr | Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| title_full_unstemmed | Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| title_short | Evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| title_sort | evaluation of semen parameters and histopathological comparison of inguinal and abdominal orchiectomy specimens in late post pubertal men with unilateral undescended testis |
| topic | Undescended Testis Orchiectomy Fertility Histology Testicular cancer |
| url | https://doi.org/10.1186/s12610-025-00270-5 |
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