Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study

Abstract Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven virulence factor that can be targeted for the design of antibacterial molecules or vaccines. Recent single-mol...

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Bibliographic Details
Main Authors: Francesca Pancrazi, Omar De Bei, Francesco Lavecchia di Tocco, Marialaura Marchetti, Barbara Campanini, Salvatore Cannistraro, Stefano Bettati, Anna Rita Bizzarri
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Nano
Online Access:https://doi.org/10.1186/s11671-025-04182-1
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