Randomised placebo-controlled multicentre trial to evaluate the efficacy and safety of JTR-161, allogeneic human dental pulp stem cells, in patients with Acute Ischaemic stRoke (J-REPAIR)

Randomised placebo-controlled multicentre trial to evaluate the efficacy and safety of JTR-161, allogeneic human dental pulp stem cells, in patients with Acute Ischaemic stRoke (J-REPAIR)

Introduction JTR-161 is a novel allogeneic human cell product consisting of dental pulp stem cells isolated from the extracted teeth of healthy adults. It is currently under development as a cell-based therapy for ischaemic stroke. The aim of this study is to evaluate the safety and efficacy of JTR-...

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Main Authors: Hideo Hara, Nobuyuki Sakai, Shinichi Yoshimura, Masafumi Ihara, Satoshi Suda, Chikako Nito, Kazumi Kimura, Yuji Matsumaru, Taketo Hatano, Masaki Takao, Takeshi Yoshimoto, Masahiro Yasaka, Masafumi Morimoto, Akira Tsujino, Takeshi Inoue, Seiji Okubo, Mitsuyasu Kanai, Kenichi Morita, Yuka Terasawa, Yasuyuki Iguchi, Takao Urabe, Masataka Takeuchi, Shinichi Takahashi, Yasuhisa Akaiwa, Norihiro Ishii, Takao Kanzawa, Eiichiro Kamatsuka, Takeshi Iwanaga, Ryuzaburo Kanazawa, Norimichi Nakamura, Yutaka Honma, Tomohiko Izumidani, Shoji Arihiro, Takayuki Mizunari
Format: Article
Language:English
Published: BMJ Publishing Group 2022-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/5/e054269.full
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