Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits
Growth traits belong to the most important economic traits in livestock. One of the genes involved in vertebrate growth and development is insulin-like growth factor 1 (IGF1). Therefore, in our study we hypothesised that within the sequence of rabbit IGF1 gene it is possible to identify a polymorphi...
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Czech Academy of Agricultural Sciences
2025-01-01
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| Series: | Czech Journal of Animal Science |
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| Online Access: | https://cjas.agriculturejournals.cz/artkey/cjs-202501-0004_association-between-polymorphism-within-rabbit-igf1-gene-and-slaughter-weight-in-termond-white-rabbits.php |
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| author | Anna Migdał Sylwia Ewa Pałka Michał Kmiecik Olga Jarnecka Ewelina Semik-Gurgul Łukasz Migdał |
| author_facet | Anna Migdał Sylwia Ewa Pałka Michał Kmiecik Olga Jarnecka Ewelina Semik-Gurgul Łukasz Migdał |
| author_sort | Anna Migdał |
| collection | DOAJ |
| description | Growth traits belong to the most important economic traits in livestock. One of the genes involved in vertebrate growth and development is insulin-like growth factor 1 (IGF1). Therefore, in our study we hypothesised that within the sequence of rabbit IGF1 gene it is possible to identify a polymorphism that may influence growth, carcass or meat traits in rabbits. We identified 6 polymorphisms (g.89259430T>C; g.89259338C>G; g.89259328T>C; 89210029A>G; 89210349C>G and g.89194199C>T) within introns of the IGF1 gene. One polymorphism, g.89194199C>T, was analysed using polymerase chain reaction high-resolution melting (PCR-HRM). We performed the association analysis on 370 animals (males to females 1 : 1) of different breeds: New Zealand White × Flemish Giant crossbreds (NZW × FG), Termond White (TW) and Flemish Giant (FG). Results showed that for growth and slaughter traits in TW populations a significant association (P = 0.003) was found for slaughter weight (SW) when CT genotypes showed significantly higher values compared to CC genotypes (2 878.0 g ± 107.0 and 2 678.0 g ± 34.0, respectively). For TW rabbits we found a significant association (P = 0.009) for dissected bone weight in hind leg (HB) when CT genotypes (127.0 g ± 5.8) had significantly higher values compared to CC genotypes (112.0 g ± 2.4). For carcass traits and physical characteristics of meat we found for musculus longissimus lumborum in TW rabbits that the b* parameter value 45 min after slaughter was significantly higher (P = 0.001) for CT genotypes (1.88 ± 0.05) compared to CC genotypes (0.05 ± 0.02). We conclude that the use of identified SNP in breeding may be limited to some breeds. |
| format | Article |
| id | doaj-art-4bd0e9698ccb4fd3aadc8e962680cb3f |
| institution | DOAJ |
| issn | 1212-1819 1805-9309 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Czech Academy of Agricultural Sciences |
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| series | Czech Journal of Animal Science |
| spelling | doaj-art-4bd0e9698ccb4fd3aadc8e962680cb3f2025-08-20T02:45:15ZengCzech Academy of Agricultural SciencesCzech Journal of Animal Science1212-18191805-93092025-01-01701334110.17221/59/2024-CJAScjs-202501-0004Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbitsAnna Migdał0Sylwia Ewa Pałka1Michał Kmiecik2Olga Jarnecka3Ewelina Semik-Gurgul4Łukasz Migdał5Department of Genetics, Animal Breeding and Ethology, University of Agriculture in Krakow, Krakow, PolandDepartment of Genetics, Animal Breeding and Ethology, University of Agriculture in Krakow, Krakow, PolandDepartment of Genetics, Animal Breeding and Ethology, University of Agriculture in Krakow, Krakow, PolandDepartment of Genetics, Animal Breeding and Ethology, University of Agriculture in Krakow, Krakow, PolandDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Balice, PolandDepartment of Genetics, Animal Breeding and Ethology, University of Agriculture in Krakow, Krakow, PolandGrowth traits belong to the most important economic traits in livestock. One of the genes involved in vertebrate growth and development is insulin-like growth factor 1 (IGF1). Therefore, in our study we hypothesised that within the sequence of rabbit IGF1 gene it is possible to identify a polymorphism that may influence growth, carcass or meat traits in rabbits. We identified 6 polymorphisms (g.89259430T>C; g.89259338C>G; g.89259328T>C; 89210029A>G; 89210349C>G and g.89194199C>T) within introns of the IGF1 gene. One polymorphism, g.89194199C>T, was analysed using polymerase chain reaction high-resolution melting (PCR-HRM). We performed the association analysis on 370 animals (males to females 1 : 1) of different breeds: New Zealand White × Flemish Giant crossbreds (NZW × FG), Termond White (TW) and Flemish Giant (FG). Results showed that for growth and slaughter traits in TW populations a significant association (P = 0.003) was found for slaughter weight (SW) when CT genotypes showed significantly higher values compared to CC genotypes (2 878.0 g ± 107.0 and 2 678.0 g ± 34.0, respectively). For TW rabbits we found a significant association (P = 0.009) for dissected bone weight in hind leg (HB) when CT genotypes (127.0 g ± 5.8) had significantly higher values compared to CC genotypes (112.0 g ± 2.4). For carcass traits and physical characteristics of meat we found for musculus longissimus lumborum in TW rabbits that the b* parameter value 45 min after slaughter was significantly higher (P = 0.001) for CT genotypes (1.88 ± 0.05) compared to CC genotypes (0.05 ± 0.02). We conclude that the use of identified SNP in breeding may be limited to some breeds.https://cjas.agriculturejournals.cz/artkey/cjs-202501-0004_association-between-polymorphism-within-rabbit-igf1-gene-and-slaughter-weight-in-termond-white-rabbits.phpassociation analysisgrowth traitsinsulin like growth factor 1meat traits oryctolagus cuniculussnp |
| spellingShingle | Anna Migdał Sylwia Ewa Pałka Michał Kmiecik Olga Jarnecka Ewelina Semik-Gurgul Łukasz Migdał Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits Czech Journal of Animal Science association analysis growth traits insulin like growth factor 1 meat traits oryctolagus cuniculus snp |
| title | Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits |
| title_full | Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits |
| title_fullStr | Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits |
| title_full_unstemmed | Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits |
| title_short | Association between polymorphism within rabbit IGF1 gene and slaughter weight in Termond White rabbits |
| title_sort | association between polymorphism within rabbit igf1 gene and slaughter weight in termond white rabbits |
| topic | association analysis growth traits insulin like growth factor 1 meat traits oryctolagus cuniculus snp |
| url | https://cjas.agriculturejournals.cz/artkey/cjs-202501-0004_association-between-polymorphism-within-rabbit-igf1-gene-and-slaughter-weight-in-termond-white-rabbits.php |
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