Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients

Conclusion: We observed blaCTX-M as the most common ESBL genotype, in combination with other ESBL genes present in some E. coli isolates. Nitrofurantoin and ceftriaxone antibiotics were efficacious. Appropriate prescription of antibiotic therapy, and the prevention of transmission of resistant genes...

Full description

Saved in:
Bibliographic Details
Main Authors: David Nana Adjei, Thomas Stuart Mughogho, Olu-Taiwo Michael, Sarah Saidu, Gloria Amegatcher, Akua Obeng Forson
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/ijm/3694023
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1825199945590767616
author David Nana Adjei
Thomas Stuart Mughogho
Olu-Taiwo Michael
Sarah Saidu
Gloria Amegatcher
Akua Obeng Forson
author_facet David Nana Adjei
Thomas Stuart Mughogho
Olu-Taiwo Michael
Sarah Saidu
Gloria Amegatcher
Akua Obeng Forson
author_sort David Nana Adjei
collection DOAJ
description Conclusion: We observed blaCTX-M as the most common ESBL genotype, in combination with other ESBL genes present in some E. coli isolates. Nitrofurantoin and ceftriaxone antibiotics were efficacious. Appropriate prescription of antibiotic therapy, and the prevention of transmission of resistant genes in the context of public health can be facilitated by routine monitoring of the resistance profiles and ESBL markers in patients with and without diabetes.
format Article
id doaj-art-4bbbc0cc2695430db504b813cf5418ab
institution Kabale University
issn 1687-9198
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series International Journal of Microbiology
spelling doaj-art-4bbbc0cc2695430db504b813cf5418ab2025-02-08T00:00:03ZengWileyInternational Journal of Microbiology1687-91982025-01-01202510.1155/ijm/3694023Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic PatientsDavid Nana Adjei0Thomas Stuart Mughogho1Olu-Taiwo Michael2Sarah Saidu3Gloria Amegatcher4Akua Obeng Forson5Department of Medical Laboratory ScienceDepartment of Medical Laboratory ScienceDepartment of Medical Laboratory ScienceDepartment of Medical Laboratory ScienceDepartment of Medical Laboratory ScienceDepartment of Medical Laboratory ScienceConclusion: We observed blaCTX-M as the most common ESBL genotype, in combination with other ESBL genes present in some E. coli isolates. Nitrofurantoin and ceftriaxone antibiotics were efficacious. Appropriate prescription of antibiotic therapy, and the prevention of transmission of resistant genes in the context of public health can be facilitated by routine monitoring of the resistance profiles and ESBL markers in patients with and without diabetes.http://dx.doi.org/10.1155/ijm/3694023
spellingShingle David Nana Adjei
Thomas Stuart Mughogho
Olu-Taiwo Michael
Sarah Saidu
Gloria Amegatcher
Akua Obeng Forson
Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
International Journal of Microbiology
title Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
title_full Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
title_fullStr Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
title_full_unstemmed Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
title_short Characterization of the Phenotypic and Genotypic Antibiotic Resistance Markers in Escherichia coli (E. coli) Associated With Diabetes and Nondiabetic Patients
title_sort characterization of the phenotypic and genotypic antibiotic resistance markers in escherichia coli e coli associated with diabetes and nondiabetic patients
url http://dx.doi.org/10.1155/ijm/3694023
work_keys_str_mv AT davidnanaadjei characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients
AT thomasstuartmughogho characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients
AT olutaiwomichael characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients
AT sarahsaidu characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients
AT gloriaamegatcher characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients
AT akuaobengforson characterizationofthephenotypicandgenotypicantibioticresistancemarkersinescherichiacoliecoliassociatedwithdiabetesandnondiabeticpatients