Angiostrongylosis meningomyelitis without blood eosinophilia
Angiostrongylus cantonensis and Gnathostoma spinigerum usually cause eosinophilic meningitis with associated peripheral blood eosinophilia. A 44-year-old man developed acute paraplegia with bowel and bladder dysfunction. Spinal magnetic resonance images showed a long T2W hyperintensity signal from...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2021-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/14975 |
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| author | Thanyalak Amornpojnimman Nuttha Sanghan Nichanan Ekpitakdamrong Prut Koonalinthip Sumonthip Leelawai Pornchai Sathirapanya |
| author_facet | Thanyalak Amornpojnimman Nuttha Sanghan Nichanan Ekpitakdamrong Prut Koonalinthip Sumonthip Leelawai Pornchai Sathirapanya |
| author_sort | Thanyalak Amornpojnimman |
| collection | DOAJ |
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Angiostrongylus cantonensis and Gnathostoma spinigerum usually cause eosinophilic meningitis with associated peripheral blood eosinophilia. A 44-year-old man developed acute paraplegia with bowel and bladder dysfunction. Spinal magnetic resonance images showed a long T2W hyperintensity signal from the 1st to 8th spinal thoracic level. Cerebrospinal fluid analysis revealed eosinophilia and elevated cerebrospinal fluid protein, whereas differential leucocytes count in peripheral blood was unremarkable. Positive immunoblot tests for A. cantonensis antibody in serum and cerebrospinal fluid were reported. The patient had neither history of recent traveling to the high endemic areas of the parasite in Thailand, nor consumption the parasitic hosts. Immediate treatment with intravenous pulse methylprednisolone and oral albendazole resulted in complete recovery. Despite an unremarkable differential leucocytes count, absence a history of parasitic hosts consumption, and a less common presentation with meningomyelitis, A. cantonensis should be considered when cerebrospinal fluid eosinophilia presents.
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| format | Article |
| id | doaj-art-4b998f635f9f4ec0a07c85bcd65bcd10 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-4b998f635f9f4ec0a07c85bcd65bcd102025-08-20T02:14:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802021-12-01151210.3855/jidc.14975Angiostrongylosis meningomyelitis without blood eosinophiliaThanyalak Amornpojnimman0Nuttha Sanghan1Nichanan Ekpitakdamrong2Prut Koonalinthip3Sumonthip Leelawai4Pornchai Sathirapanya5Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDepartment of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, ThailandDivision of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand Angiostrongylus cantonensis and Gnathostoma spinigerum usually cause eosinophilic meningitis with associated peripheral blood eosinophilia. A 44-year-old man developed acute paraplegia with bowel and bladder dysfunction. Spinal magnetic resonance images showed a long T2W hyperintensity signal from the 1st to 8th spinal thoracic level. Cerebrospinal fluid analysis revealed eosinophilia and elevated cerebrospinal fluid protein, whereas differential leucocytes count in peripheral blood was unremarkable. Positive immunoblot tests for A. cantonensis antibody in serum and cerebrospinal fluid were reported. The patient had neither history of recent traveling to the high endemic areas of the parasite in Thailand, nor consumption the parasitic hosts. Immediate treatment with intravenous pulse methylprednisolone and oral albendazole resulted in complete recovery. Despite an unremarkable differential leucocytes count, absence a history of parasitic hosts consumption, and a less common presentation with meningomyelitis, A. cantonensis should be considered when cerebrospinal fluid eosinophilia presents. https://jidc.org/index.php/journal/article/view/14975myelitiscerebrospinal fluidAngiostrongyliasis |
| spellingShingle | Thanyalak Amornpojnimman Nuttha Sanghan Nichanan Ekpitakdamrong Prut Koonalinthip Sumonthip Leelawai Pornchai Sathirapanya Angiostrongylosis meningomyelitis without blood eosinophilia Journal of Infection in Developing Countries myelitis cerebrospinal fluid Angiostrongyliasis |
| title | Angiostrongylosis meningomyelitis without blood eosinophilia |
| title_full | Angiostrongylosis meningomyelitis without blood eosinophilia |
| title_fullStr | Angiostrongylosis meningomyelitis without blood eosinophilia |
| title_full_unstemmed | Angiostrongylosis meningomyelitis without blood eosinophilia |
| title_short | Angiostrongylosis meningomyelitis without blood eosinophilia |
| title_sort | angiostrongylosis meningomyelitis without blood eosinophilia |
| topic | myelitis cerebrospinal fluid Angiostrongyliasis |
| url | https://jidc.org/index.php/journal/article/view/14975 |
| work_keys_str_mv | AT thanyalakamornpojnimman angiostrongylosismeningomyelitiswithoutbloodeosinophilia AT nutthasanghan angiostrongylosismeningomyelitiswithoutbloodeosinophilia AT nichananekpitakdamrong angiostrongylosismeningomyelitiswithoutbloodeosinophilia AT prutkoonalinthip angiostrongylosismeningomyelitiswithoutbloodeosinophilia AT sumonthipleelawai angiostrongylosismeningomyelitiswithoutbloodeosinophilia AT pornchaisathirapanya angiostrongylosismeningomyelitiswithoutbloodeosinophilia |