Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction

A 66-year-old woman presented to the hospital with a one-month history of shortness of breath, fatigue, and postmenopausal vaginal bleeding and a one-week history of chest pain. This case report discusses the rare synchronous occurrence of two different malignancies in the setting of non-ST segment...

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Main Authors: Michelle Bernshteyn, Alexandria Smith-Hannah, Amit S. Dhamoon
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2020/6192754
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author Michelle Bernshteyn
Alexandria Smith-Hannah
Amit S. Dhamoon
author_facet Michelle Bernshteyn
Alexandria Smith-Hannah
Amit S. Dhamoon
author_sort Michelle Bernshteyn
collection DOAJ
description A 66-year-old woman presented to the hospital with a one-month history of shortness of breath, fatigue, and postmenopausal vaginal bleeding and a one-week history of chest pain. This case report discusses the rare synchronous occurrence of two different malignancies in the setting of non-ST segment elevation myocardial infarction and the relation between these unfortunate events. Besides the case presented in this report, there have been only 13 reported cases of synchronous chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) associated with metastatic squamous cell carcinoma. While it is well known that malignancy causes a hypercoagulable state, there are other mechanisms which may have contributed to the patient’s myocardial ischemia including external vascular compression, tumor lysis syndrome, and anemia. This case report discusses the rarity of synchronous malignancies but the importance of understanding and consideration of cardiac events in this population.
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publishDate 2020-01-01
publisher Wiley
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series Case Reports in Oncological Medicine
spelling doaj-art-4b96b3b457ca415f9161041f4d3d64f82025-02-03T06:46:00ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/61927546192754Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial InfarctionMichelle Bernshteyn0Alexandria Smith-Hannah1Amit S. Dhamoon2SUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USASUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USASUNY Upstate Medical University Hospital, 750 E Adams St., Syracuse, NY 13210, USAA 66-year-old woman presented to the hospital with a one-month history of shortness of breath, fatigue, and postmenopausal vaginal bleeding and a one-week history of chest pain. This case report discusses the rare synchronous occurrence of two different malignancies in the setting of non-ST segment elevation myocardial infarction and the relation between these unfortunate events. Besides the case presented in this report, there have been only 13 reported cases of synchronous chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) associated with metastatic squamous cell carcinoma. While it is well known that malignancy causes a hypercoagulable state, there are other mechanisms which may have contributed to the patient’s myocardial ischemia including external vascular compression, tumor lysis syndrome, and anemia. This case report discusses the rarity of synchronous malignancies but the importance of understanding and consideration of cardiac events in this population.http://dx.doi.org/10.1155/2020/6192754
spellingShingle Michelle Bernshteyn
Alexandria Smith-Hannah
Amit S. Dhamoon
Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
Case Reports in Oncological Medicine
title Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
title_full Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
title_fullStr Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
title_full_unstemmed Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
title_short Synchronous Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and Metastatic Squamous Cell Carcinoma of the Cervix Involving the Coronary Arteries Leading to Acute Myocardial Infarction
title_sort synchronous chronic lymphocytic leukemia small lymphocytic lymphoma and metastatic squamous cell carcinoma of the cervix involving the coronary arteries leading to acute myocardial infarction
url http://dx.doi.org/10.1155/2020/6192754
work_keys_str_mv AT michellebernshteyn synchronouschroniclymphocyticleukemiasmalllymphocyticlymphomaandmetastaticsquamouscellcarcinomaofthecervixinvolvingthecoronaryarteriesleadingtoacutemyocardialinfarction
AT alexandriasmithhannah synchronouschroniclymphocyticleukemiasmalllymphocyticlymphomaandmetastaticsquamouscellcarcinomaofthecervixinvolvingthecoronaryarteriesleadingtoacutemyocardialinfarction
AT amitsdhamoon synchronouschroniclymphocyticleukemiasmalllymphocyticlymphomaandmetastaticsquamouscellcarcinomaofthecervixinvolvingthecoronaryarteriesleadingtoacutemyocardialinfarction