Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong
Background: Wheeze has been reported to affect one-third of preschoolchildren. While different wheeze patterns have been shown to predict future asthma risk, limited data are available on the risk factors for preschool wheeze in Asia. Methods: Preschool children admitted to hospitals through emergen...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Pediatric Respirology and Critical Care Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/prcm.prcm_23_17 |
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| _version_ | 1850177490293620736 |
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| author | Ka-Ka Siu Chin-Pang Wong Rachel Shui-Ping Lee Jack Pak-Yeung Chan Shuk-Yu Leung Eric Yat-Tung Chan Ka-Li Kwok Ada Yuen-Fong Yip Rupert Phillips Daniel Kwok-Keung Ng |
| author_facet | Ka-Ka Siu Chin-Pang Wong Rachel Shui-Ping Lee Jack Pak-Yeung Chan Shuk-Yu Leung Eric Yat-Tung Chan Ka-Li Kwok Ada Yuen-Fong Yip Rupert Phillips Daniel Kwok-Keung Ng |
| author_sort | Ka-Ka Siu |
| collection | DOAJ |
| description | Background:
Wheeze has been reported to affect one-third of preschoolchildren. While different wheeze patterns have been shown to predict future asthma risk, limited data are available on the risk factors for preschool wheeze in Asia.
Methods:
Preschool children admitted to hospitals through emergency departments for wheeze, from 2004 to 2015 in Hong Kong, were retrospectively identified. Potential risk factors for admissions over the same period were retrieved (i.e., air pollutants, preterm delivery, and maternal age).
Results:
A total of 46,258 patients meeting the inclusion criteria were identified during the 12-year period. The preschool wheeze admission rate increased by 34% over the past 12 years, with an average year-on-year rise of 4.2%. Environmental nitrogen dioxide (NO2) concentration was significantly associated with an increase in admission for preschool wheeze (r = 0.63, P = 0.028). Univariate regression analysis was performed on potential risk factors. Annual average NO2concentration (P = 0.007) and maternal age more than 40 years (P = 0.012) were significant risk factors. For multivariable regression analysis, annual average NO2concentration (β = 0.18, 95% confidence interval = 0.06–0.30) was the only independent factor associated with preschool wheeze admission.
Conclusions:
The increase of NO2concentration is a significant risk factor for the increase in hospitalizations for preschool wheeze in Hong Kong. |
| format | Article |
| id | doaj-art-4b87a6d8bcbf45c4b5b4ebffcbd4c438 |
| institution | OA Journals |
| issn | 2543-0343 2543-0351 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pediatric Respirology and Critical Care Medicine |
| spelling | doaj-art-4b87a6d8bcbf45c4b5b4ebffcbd4c4382025-08-20T02:18:58ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512018-01-0121111510.4103/prcm.prcm_23_17Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong KongKa-Ka SiuChin-Pang WongRachel Shui-Ping LeeJack Pak-Yeung ChanShuk-Yu LeungEric Yat-Tung ChanKa-Li KwokAda Yuen-Fong YipRupert PhillipsDaniel Kwok-Keung NgBackground: Wheeze has been reported to affect one-third of preschoolchildren. While different wheeze patterns have been shown to predict future asthma risk, limited data are available on the risk factors for preschool wheeze in Asia. Methods: Preschool children admitted to hospitals through emergency departments for wheeze, from 2004 to 2015 in Hong Kong, were retrospectively identified. Potential risk factors for admissions over the same period were retrieved (i.e., air pollutants, preterm delivery, and maternal age). Results: A total of 46,258 patients meeting the inclusion criteria were identified during the 12-year period. The preschool wheeze admission rate increased by 34% over the past 12 years, with an average year-on-year rise of 4.2%. Environmental nitrogen dioxide (NO2) concentration was significantly associated with an increase in admission for preschool wheeze (r = 0.63, P = 0.028). Univariate regression analysis was performed on potential risk factors. Annual average NO2concentration (P = 0.007) and maternal age more than 40 years (P = 0.012) were significant risk factors. For multivariable regression analysis, annual average NO2concentration (β = 0.18, 95% confidence interval = 0.06–0.30) was the only independent factor associated with preschool wheeze admission. Conclusions: The increase of NO2concentration is a significant risk factor for the increase in hospitalizations for preschool wheeze in Hong Kong.https://journals.lww.com/10.4103/prcm.prcm_23_17bronchiolitispollutantswheezing |
| spellingShingle | Ka-Ka Siu Chin-Pang Wong Rachel Shui-Ping Lee Jack Pak-Yeung Chan Shuk-Yu Leung Eric Yat-Tung Chan Ka-Li Kwok Ada Yuen-Fong Yip Rupert Phillips Daniel Kwok-Keung Ng Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong Pediatric Respirology and Critical Care Medicine bronchiolitis pollutants wheezing |
| title | Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong |
| title_full | Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong |
| title_fullStr | Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong |
| title_full_unstemmed | Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong |
| title_short | Air Pollution as a Risk Factor for Increasing Hospitalizations of Preschool Wheeze in Hong Kong |
| title_sort | air pollution as a risk factor for increasing hospitalizations of preschool wheeze in hong kong |
| topic | bronchiolitis pollutants wheezing |
| url | https://journals.lww.com/10.4103/prcm.prcm_23_17 |
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