Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression
Heightened trait impulsivity in both subclinical and pathological senses is becoming increasingly recognised in Parkinson’s disease (PD). Impulsive behaviours and impulse control disorders (ICDs) are a consequence of perturbation to the rewards pathway leading individuals to conduct activities in a...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2024/8770997 |
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| author | Holly Spencer Ryan S. Anderton |
| author_facet | Holly Spencer Ryan S. Anderton |
| author_sort | Holly Spencer |
| collection | DOAJ |
| description | Heightened trait impulsivity in both subclinical and pathological senses is becoming increasingly recognised in Parkinson’s disease (PD). Impulsive behaviours and impulse control disorders (ICDs) are a consequence of perturbation to the rewards pathway leading individuals to conduct activities in a repetitive, excessive, and maladaptive fashion. Commonly linked to PD, heightened trait impulsivity has been found to primarily manifest in the forms of hypersexuality, pathological gambling, compulsive shopping, and binge eating, all of which may significantly impact social and financial standing. Subsequent burden to quality of life for both individuals with PD and caregivers are common. Although risk factors and indicators for ICDs in PD are currently lacking, it is recognised that the condition is often precipitated by dopamine replacement therapies, primarily dopamine agonist administration. While this nonmotor symptom is being increasingly diagnosed in PD populations, it remains relatively elusive in comparison to its motor counterparts. Through discussion of impulsivity characteristics, neuroanatomy, and neurochemistry, in addition to reviewing existing research on the potential contributing factors to impulsivity in PD, this review highlights impulsivity as a significant and detrimental PD symptom. Thus, emphasising the imperative need to establish efficacious diagnostic tools and treatments. |
| format | Article |
| id | doaj-art-4b6ce3d7ffb7439f9c53930e4e751027 |
| institution | OA Journals |
| issn | 2042-0080 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-4b6ce3d7ffb7439f9c53930e4e7510272025-08-20T02:38:35ZengWileyParkinson's Disease2042-00802024-01-01202410.1155/2024/8770997Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and ProgressionHolly Spencer0Ryan S. Anderton1School of Health SciencesSchool of Health SciencesHeightened trait impulsivity in both subclinical and pathological senses is becoming increasingly recognised in Parkinson’s disease (PD). Impulsive behaviours and impulse control disorders (ICDs) are a consequence of perturbation to the rewards pathway leading individuals to conduct activities in a repetitive, excessive, and maladaptive fashion. Commonly linked to PD, heightened trait impulsivity has been found to primarily manifest in the forms of hypersexuality, pathological gambling, compulsive shopping, and binge eating, all of which may significantly impact social and financial standing. Subsequent burden to quality of life for both individuals with PD and caregivers are common. Although risk factors and indicators for ICDs in PD are currently lacking, it is recognised that the condition is often precipitated by dopamine replacement therapies, primarily dopamine agonist administration. While this nonmotor symptom is being increasingly diagnosed in PD populations, it remains relatively elusive in comparison to its motor counterparts. Through discussion of impulsivity characteristics, neuroanatomy, and neurochemistry, in addition to reviewing existing research on the potential contributing factors to impulsivity in PD, this review highlights impulsivity as a significant and detrimental PD symptom. Thus, emphasising the imperative need to establish efficacious diagnostic tools and treatments.http://dx.doi.org/10.1155/2024/8770997 |
| spellingShingle | Holly Spencer Ryan S. Anderton Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression Parkinson's Disease |
| title | Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression |
| title_full | Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression |
| title_fullStr | Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression |
| title_full_unstemmed | Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression |
| title_short | Trait Impulsivity as a Feature of Parkinson’s Disease Treatment and Progression |
| title_sort | trait impulsivity as a feature of parkinson s disease treatment and progression |
| url | http://dx.doi.org/10.1155/2024/8770997 |
| work_keys_str_mv | AT hollyspencer traitimpulsivityasafeatureofparkinsonsdiseasetreatmentandprogression AT ryansanderton traitimpulsivityasafeatureofparkinsonsdiseasetreatmentandprogression |