Impact of adjunctive tolvaptan on sympathetic activity in acute heart failure with preserved ejection fraction

Impact of adjunctive tolvaptan on sympathetic activity in acute heart failure with preserved ejection fraction

Abstract Aims Acute decompensated heart failure (ADHF) is generally treated by decongestion using diuretic therapy. However, the use of loop diuretics is associated with increased cardiac sympathetic nerve activity (CSNA). We aimed to evaluate the effect of adjunctive tolvaptan therapy on CSNA in AD...

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Main Authors: Shunsuke Tamaki, Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Masahiro Seo, Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Masatsugu Kawahira, Kazuya Tanabe, Kunpei Ueda, Takanari Kimura, Daisuke Sakamoto, Yuto Tamura, Takeshi Fujita, Masatake Fukunami
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:ESC Heart Failure
Subjects:
Acute decompensated heart failure
Congestion
Sympathetic nerve activity
Tolvaptan
Online Access:https://doi.org/10.1002/ehf2.12690
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