RING finger protein 5 is a key anti-FMDV host factor through inhibition of virion assembly.
Foot-and-mouth disease virus (FMDV) are small, icosahedral viruses that cause serious clinical symptoms in livestock. The FMDV VP1 protein is a key structural component, facilitating virus entry. Here, we find that the E3 ligase RNF5 interacts with VP1 and targets it for degradation through ubiquiti...
Saved in:
| Main Authors: | Wei Zhang, Weiwei Li, Yang Yang, Weijun Cao, Wenhua Shao, Mengyao Huang, Jiali Wang, Zhitong Chen, Jiantao Cai, Hongyi Liu, Xiaoyi Zhao, Xingyan Dong, Tingting Zhou, Hong Tian, Zixiang Zhu, Fan Yang, Haixue Zheng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1012848 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Phospholipase PLA2G16 Accelerates the Host Interferon Signaling Pathway Response to FMDV
by: Bingjie Sun, et al.
Published: (2025-06-01) -
β-Coronaviruses exploit ESCRT for virion assembly and egress
by: Yuanyuan Zhang, et al.
Published: (2025-06-01) -
The role of HIV-1 Gag and genomic RNA interactions in virion assembly
by: Takaaki Koma, et al.
Published: (2025-08-01) -
Efficacy of Recombinant Genetic Diagnostic Tools for Foot-and-Mouth Disease Virus (FMDV)
by: Mai M. Abd El-Rahman, et al.
Published: (2024-12-01) -
Hepatitis C Virus E2 Protein Ectodomain Is Essential for Assembly of Infectious Virions
by: Alessia Bianchi, et al.
Published: (2011-01-01)