Brain MRI and regional vulnerabilities to radiation necrosis: investigating the impact of stereotactic radiotherapy in brain metastases treatment

Brain MRI and regional vulnerabilities to radiation necrosis: investigating the impact of stereotactic radiotherapy in brain metastases treatment

BackgroundRadiation necrosis is a significant late adverse effect of stereotactic radiotherapy (fSRT) for brain metastases, characterized by inflammatory processes and necrotic degeneration of healthy brain tissue.ObjectiveTo evaluate the relationship between the incidence of radiation necrosis and...

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Bibliographic Details
Main Authors: Carlo A. Mallio, Ugo Ferrari, Gianfranco Di Gennaro, Matteo Pileri, Caterina Bernetti, Enrica Polo, Emma Gangemi, Francesca Giannetti, Paolo Matteucci, Bruno Beomonte Zobel, Edy Ippolito, Sara Ramella
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Radiology
Subjects:
brain MRI
radiation necrosis
stem cell niches
stereotactic radiotherapy
brain metastases
Online Access:https://www.frontiersin.org/articles/10.3389/fradi.2025.1554017/full
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