Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem
We report a case of a young patient in whom a sirolimus-eluting stent was implanted on the culprit left anterior descending coronary artery at primary percutaneous coronary intervention (PCI) for acute myocardial infarction. Nine months later she suffered from a reinfarction due to the late stent th...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2009/816715 |
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| _version_ | 1849406179696967680 |
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| author | Igor Kranjec Andreja Cerne |
| author_facet | Igor Kranjec Andreja Cerne |
| author_sort | Igor Kranjec |
| collection | DOAJ |
| description | We report a case of a young patient in whom a sirolimus-eluting stent was implanted on the culprit left anterior descending coronary artery at primary percutaneous coronary intervention (PCI) for acute myocardial infarction. Nine months later she suffered from a reinfarction due to the late stent thrombosis despite a continuous antiplatelet therapy with aspirin and clopidogrel. A cluster of factors that might have contributed to the development of the stent thrombosis were identified: suboptimal PCI technique, complete stent fracture, and clopidogrel resistance. The obstructed stent was successfully reopened by repeat PCI, while the clopidogrel maintenance dosage was doubled to 150 mg daily for the following year. The further long-term clinical course was uneventful. |
| format | Article |
| id | doaj-art-4b535c9b732148c8a304730f67f6f0c1 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-4b535c9b732148c8a304730f67f6f0c12025-08-20T03:36:27ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/816715816715Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial ProblemIgor Kranjec0Andreja Cerne1Department of Cardiology, University Medical Centre Ljubljana, 1000 Ljubljana, SloveniaDepartment of Cardiology, University Medical Centre Ljubljana, 1000 Ljubljana, SloveniaWe report a case of a young patient in whom a sirolimus-eluting stent was implanted on the culprit left anterior descending coronary artery at primary percutaneous coronary intervention (PCI) for acute myocardial infarction. Nine months later she suffered from a reinfarction due to the late stent thrombosis despite a continuous antiplatelet therapy with aspirin and clopidogrel. A cluster of factors that might have contributed to the development of the stent thrombosis were identified: suboptimal PCI technique, complete stent fracture, and clopidogrel resistance. The obstructed stent was successfully reopened by repeat PCI, while the clopidogrel maintenance dosage was doubled to 150 mg daily for the following year. The further long-term clinical course was uneventful.http://dx.doi.org/10.1155/2009/816715 |
| spellingShingle | Igor Kranjec Andreja Cerne Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem Case Reports in Medicine |
| title | Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem |
| title_full | Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem |
| title_fullStr | Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem |
| title_full_unstemmed | Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem |
| title_short | Late Thrombosis of Sirolimus-Eluting Stent: A Multifactorial Problem |
| title_sort | late thrombosis of sirolimus eluting stent a multifactorial problem |
| url | http://dx.doi.org/10.1155/2009/816715 |
| work_keys_str_mv | AT igorkranjec latethrombosisofsirolimuselutingstentamultifactorialproblem AT andrejacerne latethrombosisofsirolimuselutingstentamultifactorialproblem |