Establishment of knockout mutagenesis in avrBs3/pthA family genes of Xanthomonas oryzae pv. oryzicola

The contribution of at least twenty highly conserved avrBs3/pthA family genes in Xanthomonas oryz ae pv. oryzicola (Xoc) to virulence or avirulence in rice is still rudimentary. Based on the conserved structure of the avrBs3/pthA family, a marker-exchange mutagenesis strategy in association with med...

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Bibliographic Details
Main Authors: CAO Yan-fei, ZOU Li-fang, ZHAO Wen-xiang, JI Zhi-yuan, ZOU Hua-song, CHEN Gong-you
Format: Article
Language:English
Published: Zhejiang University Press 2011-01-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2011.01.006
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Summary:The contribution of at least twenty highly conserved avrBs3/pthA family genes in Xanthomonas oryz ae pv. oryzicola (Xoc) to virulence or avirulence in rice is still rudimentary. Based on the conserved structure of the avrBs3/pthA family, a marker-exchange mutagenesis strategy in association with mediation by a suicide vector pKMS1 was used to knock out the avrBs3/pthA family genes of Xoc. The results showed that total five avrBs3/pthA genes were gradually knocked out based on the conserved structure of the family by using marker-exchange mutagenesis mediated by a suicide vector pKMS1. The knock-out mutation occurred either within an avrBs3/pthA gene or between two av rBs3/pthA genes. PCR and Southern hybridization analysis demonstrated that the establishment of knock-out mutagenesis in avrBs3/pthA genes of Xoc was successful, providing a platform to assess virulence or/and avirulence roles contributed by each member of the avrBs3/pthA family in rice.
ISSN:1008-9209
2097-5155