Efficacy and safety of TACE combined with lenvatinib and PD-1 Inhibitor in intermediate-stage HCC exceeding the up-7 criteria: a retrospective cohort study

Efficacy and safety of TACE combined with lenvatinib and PD-1 Inhibitor in intermediate-stage HCC exceeding the up-7 criteria: a retrospective cohort study

PurposeThis study aimed to assess the efficacy and safety of combining transarterial chemoembolization (TACE) with lenvatinib and a PD-1 inhibitor (TACE+LEN+PD-1) compared to TACE combined with lenvatinib alone (TACE+LEN) in intermediate-stage hepatocellular carcinoma (HCC) patients exceeding the up...

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Bibliographic Details
Main Authors: Miao Xue, Yanqin Wu, Yiyang Tang, Kun Huang, Haikuan Liu, Bowen Zhu, Jie Wen, Yue Zhao, Guixiong Zhang, Hang Liu, Wenzhe Fan, Jiaping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
hepatocellular carcinoma
up-7 criteria
transarterial chemoembolization
lenvatinib
PD-1 inhibitor
combined therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560750/full
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