Metabolomic analysis of the intrinsic resistance mechanisms of Microtus fortis against Schistosoma japonicum infection

Metabolomic analysis of the intrinsic resistance mechanisms of Microtus fortis against Schistosoma japonicum infection

Abstract Microtus fortis (M. fortis) is the only mammal known in China that is intrinsically resistant to Schistosoma japonicum (S. japonicum) infection. Nevertheless, the underlying resistance mechanism of M. fortis against schistosomes are still unclear. In this study, we detected and compared col...

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Main Authors: Tianqiong He, Du Zhang, Yixin Wen, Qian Liu, Junkang Zhou, Wenling Zhi, Lingxuan OuYang, Yushan Qi, Zikang Zhou, Xin Gao, Fan Li, Zhijie Su, Jia Shen, Zhijun Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Metabolomics
Serum
Colon aqueous extracts
Schistosoma japonicum
M. fortis
ICR mice
Online Access:https://doi.org/10.1038/s41598-025-91164-z
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