Age aspect of adaptive response of the central nervous system in the state of emotional pain

The formation of higher adaptive response in the postoperative period was investigated in experiments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months) and old rats (20-24 months) with the greatear effect in animals of the first...

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Main Author: Demchenko Ye.M.
Format: Article
Language:English
Published: Dnipro State Medical University 2014-11-01
Series:Medičnì Perspektivi
Subjects:
Online Access:http://medpers.dsma.dp.ua/issues/2014/N4/12-17.pdf
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author Demchenko Ye.M.
author_facet Demchenko Ye.M.
author_sort Demchenko Ye.M.
collection DOAJ
description The formation of higher adaptive response in the postoperative period was investigated in experiments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months) and old rats (20-24 months) with the greatear effect in animals of the first age group. In young rats the inhibition of spatial memory was observed – number of food-getting depleted reactions decreased by 28%. Cognitive deficit was accompanied by opposite changes in the content of free unsaturated fatty acids (C18: 2.3), respectively to age features: decreased by 46% in the cortex of young rats and increased by 2.5-fold in the hippocampus of old animals.
format Article
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spelling doaj-art-4b39346c218146ad98bb2eb8560da3932025-08-20T01:47:48ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042307-04042014-11-011941217Age aspect of adaptive response of the central nervous system in the state of emotional painDemchenko Ye.M. 0SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»The formation of higher adaptive response in the postoperative period was investigated in experiments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months) and old rats (20-24 months) with the greatear effect in animals of the first age group. In young rats the inhibition of spatial memory was observed – number of food-getting depleted reactions decreased by 28%. Cognitive deficit was accompanied by opposite changes in the content of free unsaturated fatty acids (C18: 2.3), respectively to age features: decreased by 46% in the cortex of young rats and increased by 2.5-fold in the hippocampus of old animals.http://medpers.dsma.dp.ua/issues/2014/N4/12-17.pdfspontaneous behavioral activityspatial memoryunsaturated fatty acidshippocampusneocortex
spellingShingle Demchenko Ye.M.
Age aspect of adaptive response of the central nervous system in the state of emotional pain
Medičnì Perspektivi
spontaneous behavioral activity
spatial memory
unsaturated fatty acids
hippocampus
neocortex
title Age aspect of adaptive response of the central nervous system in the state of emotional pain
title_full Age aspect of adaptive response of the central nervous system in the state of emotional pain
title_fullStr Age aspect of adaptive response of the central nervous system in the state of emotional pain
title_full_unstemmed Age aspect of adaptive response of the central nervous system in the state of emotional pain
title_short Age aspect of adaptive response of the central nervous system in the state of emotional pain
title_sort age aspect of adaptive response of the central nervous system in the state of emotional pain
topic spontaneous behavioral activity
spatial memory
unsaturated fatty acids
hippocampus
neocortex
url http://medpers.dsma.dp.ua/issues/2014/N4/12-17.pdf
work_keys_str_mv AT demchenkoyem ageaspectofadaptiveresponseofthecentralnervoussysteminthestateofemotionalpain