The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women

(1) Background: Copper is a crucial trace element which is vital to growth and development and is especially important in bone health. Copper intake is now the focus of much broader research beyond its associations with nail growth, looking at copper’s potential in contributing to bone integrity to...

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Main Authors: María Luz Canal-Macías, Luis Manuel Puerto-Parejo, Jesús María Lavado-García, Raúl Roncero-Martín, Juan Diego Pedrera-Zamorano, Fidel López-Espuela, Purificación Rey-Sánchez, Antonio Sánchez-Fernández, José M. Morán
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:European Journal of Investigation in Health, Psychology and Education
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Online Access:https://www.mdpi.com/2254-9625/15/2/25
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author María Luz Canal-Macías
Luis Manuel Puerto-Parejo
Jesús María Lavado-García
Raúl Roncero-Martín
Juan Diego Pedrera-Zamorano
Fidel López-Espuela
Purificación Rey-Sánchez
Antonio Sánchez-Fernández
José M. Morán
author_facet María Luz Canal-Macías
Luis Manuel Puerto-Parejo
Jesús María Lavado-García
Raúl Roncero-Martín
Juan Diego Pedrera-Zamorano
Fidel López-Espuela
Purificación Rey-Sánchez
Antonio Sánchez-Fernández
José M. Morán
author_sort María Luz Canal-Macías
collection DOAJ
description (1) Background: Copper is a crucial trace element which is vital to growth and development and is especially important in bone health. Copper intake is now the focus of much broader research beyond its associations with nail growth, looking at copper’s potential in contributing to bone integrity to prevent a high risk of osteoporosis as well. (2) Methods: This study included postmenopausal women from a larger longitudinal study conducted between 2019 and 2022. Bone health was assessed using three quantitative techniques: heel QUS, DXA and pQCT. Copper intake was evaluated using a 131-item, 7-day food frequency questionnaire. Data from these assessments were used to analyze the relationship between copper intake and bone health. (3) Results: In the unadjusted multiple linear regression model, associations were found between copper intake levels and both BUA (dB/MHz) and pQCT cortical + subcortical density (mg/cm<sup>3</sup>), with copper intake acting as a negative predictor in both instances. However, these associations lost statistical significance after adjusting for participant age and weight. No further associations were identified for the other parameters assessed. (4) We conclude that our study does not reveal an association between copper intake and bone health in postmenopausal Spanish women.
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spelling doaj-art-4b2e15ec735b45629a97f56f9b36bc692025-08-20T02:44:49ZengMDPI AGEuropean Journal of Investigation in Health, Psychology and Education2174-81442254-96252025-02-011522510.3390/ejihpe15020025The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish WomenMaría Luz Canal-Macías0Luis Manuel Puerto-Parejo1Jesús María Lavado-García2Raúl Roncero-Martín3Juan Diego Pedrera-Zamorano4Fidel López-Espuela5Purificación Rey-Sánchez6Antonio Sánchez-Fernández7José M. Morán8Metabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, SpainServicio de Tocoginecologia, Hospital San Pedro de Alcántara, 10003 Caceres, SpainMetabolic Bone Diseases Research Group, Nursing Department, Nursing and Occupational Therapy College, University of Extremadura, 10003 Cceres, Spain(1) Background: Copper is a crucial trace element which is vital to growth and development and is especially important in bone health. Copper intake is now the focus of much broader research beyond its associations with nail growth, looking at copper’s potential in contributing to bone integrity to prevent a high risk of osteoporosis as well. (2) Methods: This study included postmenopausal women from a larger longitudinal study conducted between 2019 and 2022. Bone health was assessed using three quantitative techniques: heel QUS, DXA and pQCT. Copper intake was evaluated using a 131-item, 7-day food frequency questionnaire. Data from these assessments were used to analyze the relationship between copper intake and bone health. (3) Results: In the unadjusted multiple linear regression model, associations were found between copper intake levels and both BUA (dB/MHz) and pQCT cortical + subcortical density (mg/cm<sup>3</sup>), with copper intake acting as a negative predictor in both instances. However, these associations lost statistical significance after adjusting for participant age and weight. No further associations were identified for the other parameters assessed. (4) We conclude that our study does not reveal an association between copper intake and bone health in postmenopausal Spanish women.https://www.mdpi.com/2254-9625/15/2/25copperosteoporosisbone mineral densitydietary intakefood frequency questionnaire
spellingShingle María Luz Canal-Macías
Luis Manuel Puerto-Parejo
Jesús María Lavado-García
Raúl Roncero-Martín
Juan Diego Pedrera-Zamorano
Fidel López-Espuela
Purificación Rey-Sánchez
Antonio Sánchez-Fernández
José M. Morán
The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
European Journal of Investigation in Health, Psychology and Education
copper
osteoporosis
bone mineral density
dietary intake
food frequency questionnaire
title The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
title_full The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
title_fullStr The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
title_full_unstemmed The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
title_short The Role of Copper Intake in Bone Health: A Quantitative Analysis in Postmenopausal Spanish Women
title_sort role of copper intake in bone health a quantitative analysis in postmenopausal spanish women
topic copper
osteoporosis
bone mineral density
dietary intake
food frequency questionnaire
url https://www.mdpi.com/2254-9625/15/2/25
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