Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption

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Main Authors: Yuan Feng, Bin Lu, Yongheng Huang, Hui Wang, Jianliang Xu, Nan Lin
Format: Article
Language:English
Published: American Chemical Society 2025-01-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c07198
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author Yuan Feng
Bin Lu
Yongheng Huang
Hui Wang
Jianliang Xu
Nan Lin
author_facet Yuan Feng
Bin Lu
Yongheng Huang
Hui Wang
Jianliang Xu
Nan Lin
author_sort Yuan Feng
collection DOAJ
format Article
id doaj-art-4b24cf2d3f27473e8024f2e6c3f4448b
institution Kabale University
issn 2470-1343
language English
publishDate 2025-01-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-4b24cf2d3f27473e8024f2e6c3f4448b2025-01-28T09:04:07ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011032575258510.1021/acsomega.4c07198Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway DisruptionYuan FengBin LuYongheng HuangHui WangJianliang XuNan Linhttps://doi.org/10.1021/acsomega.4c07198
spellingShingle Yuan Feng
Bin Lu
Yongheng Huang
Hui Wang
Jianliang Xu
Nan Lin
Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
ACS Omega
title Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
title_full Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
title_fullStr Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
title_full_unstemmed Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
title_short Perfluorooctanoic Acid Induces Ferroptosis in Hepatocytes via Oxidative Stress and AKT/GSK3β/β-Catenin Pathway Disruption
title_sort perfluorooctanoic acid induces ferroptosis in hepatocytes via oxidative stress and akt gsk3β β catenin pathway disruption
url https://doi.org/10.1021/acsomega.4c07198
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AT binlu perfluorooctanoicacidinducesferroptosisinhepatocytesviaoxidativestressandaktgsk3bbcateninpathwaydisruption
AT yonghenghuang perfluorooctanoicacidinducesferroptosisinhepatocytesviaoxidativestressandaktgsk3bbcateninpathwaydisruption
AT huiwang perfluorooctanoicacidinducesferroptosisinhepatocytesviaoxidativestressandaktgsk3bbcateninpathwaydisruption
AT jianliangxu perfluorooctanoicacidinducesferroptosisinhepatocytesviaoxidativestressandaktgsk3bbcateninpathwaydisruption
AT nanlin perfluorooctanoicacidinducesferroptosisinhepatocytesviaoxidativestressandaktgsk3bbcateninpathwaydisruption