Nucleic acid spheres for treating capillarisation of liver sinusoidal endothelial cells in liver fibrosis

Abstract Liver sinusoidal endothelial cells (LSECs) lose their characteristic fenestrations and become capillarized during the progression of liver fibrosis. Mesenchymal stem cell (MSC) transplantation can reverse this capillarization and reduce fibrosis, but MSC therapy has practical limitations th...

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Bibliographic Details
Main Authors: Wenjia Liu, Yuting Liu, Liqiang Zhang, Liya Li, Wenguang Yang, Jia Li, Wangxiao He
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59885-x
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