Associations between physical activity and heart disease among middle-aged and older Chinese adults

ObjectiveTo quantify the risk of heart diseases (HD) and determine the relationship between physical activity (PA) dimensions and HD among Chinese middle-aged and older individuals.MethodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS, 2018), 16,927 participants were incl...

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Main Authors: Yujia Liu, Chaoqun Yuan, Tong Chen, Linlin Zhou, Gengyin Zhu, Yu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1383888/full
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author Yujia Liu
Chaoqun Yuan
Tong Chen
Linlin Zhou
Gengyin Zhu
Yu Chen
author_facet Yujia Liu
Chaoqun Yuan
Tong Chen
Linlin Zhou
Gengyin Zhu
Yu Chen
author_sort Yujia Liu
collection DOAJ
description ObjectiveTo quantify the risk of heart diseases (HD) and determine the relationship between physical activity (PA) dimensions and HD among Chinese middle-aged and older individuals.MethodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS, 2018), 16,927 participants were included in this study. Multivariate logistic regression was performed to determine the association between HD risk and PA dimensions, including volume, intensity, frequency, and duration. Restricted cubic spline analysis was conducted to assess the dose-response relationship between PA and HD risk.ResultsCompared to the least active participants, a low risk of HD was significantly associated with a higher PA volume. With regards to frequency, a lower HD risk was associated with performing vigorous PA except for 3–5 days/week. The frequency and duration of light as well as moderate PA had no significant associations with HD risk after adjusted by using covariates. A non-linear association was also noted, with increased PA being associated with decreased HD risk, with steeper reductions in HD risk at low activity levels than at high activity levels. There was a non-linear association between PA and HD risk in participants in male and aged older than 65 years.ConclusionsAn inverse non-linear dose-response association was detected between the total volume of PA and HD risk. As PA increased to 4,000 METs-min/week, HD risk in the overall population decreased by approximately 26%, while further increases in PA did not produce any further marked reduction in the risk. A vigorous intensity of PA was associated with a reduced risk of HD and is strongly recommended.
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spelling doaj-art-4b1cf08e26b44d6fb883b14d52b3b7b62025-01-24T07:13:52ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-01-011210.3389/fcvm.2025.13838881383888Associations between physical activity and heart disease among middle-aged and older Chinese adultsYujia Liu0Chaoqun Yuan1Tong Chen2Linlin Zhou3Gengyin Zhu4Yu Chen5Institute of Physical Education, Jiangsu Normal University, Xuzhou, ChinaSports Health College, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaLibrary of Jingwen, Jiangsu Normal University, Xuzhou, ChinaInstitute of Physical Education, Jiangsu Normal University, Xuzhou, ChinaCollege of Physical Education, Chongqing University, Chongqing, ChinaCollege of Physical Education, Chongqing University, Chongqing, ChinaObjectiveTo quantify the risk of heart diseases (HD) and determine the relationship between physical activity (PA) dimensions and HD among Chinese middle-aged and older individuals.MethodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS, 2018), 16,927 participants were included in this study. Multivariate logistic regression was performed to determine the association between HD risk and PA dimensions, including volume, intensity, frequency, and duration. Restricted cubic spline analysis was conducted to assess the dose-response relationship between PA and HD risk.ResultsCompared to the least active participants, a low risk of HD was significantly associated with a higher PA volume. With regards to frequency, a lower HD risk was associated with performing vigorous PA except for 3–5 days/week. The frequency and duration of light as well as moderate PA had no significant associations with HD risk after adjusted by using covariates. A non-linear association was also noted, with increased PA being associated with decreased HD risk, with steeper reductions in HD risk at low activity levels than at high activity levels. There was a non-linear association between PA and HD risk in participants in male and aged older than 65 years.ConclusionsAn inverse non-linear dose-response association was detected between the total volume of PA and HD risk. As PA increased to 4,000 METs-min/week, HD risk in the overall population decreased by approximately 26%, while further increases in PA did not produce any further marked reduction in the risk. A vigorous intensity of PA was associated with a reduced risk of HD and is strongly recommended.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1383888/fullphysical activityheart diseasemiddle-aged and older individualsdose-response relationshipintensity
spellingShingle Yujia Liu
Chaoqun Yuan
Tong Chen
Linlin Zhou
Gengyin Zhu
Yu Chen
Associations between physical activity and heart disease among middle-aged and older Chinese adults
Frontiers in Cardiovascular Medicine
physical activity
heart disease
middle-aged and older individuals
dose-response relationship
intensity
title Associations between physical activity and heart disease among middle-aged and older Chinese adults
title_full Associations between physical activity and heart disease among middle-aged and older Chinese adults
title_fullStr Associations between physical activity and heart disease among middle-aged and older Chinese adults
title_full_unstemmed Associations between physical activity and heart disease among middle-aged and older Chinese adults
title_short Associations between physical activity and heart disease among middle-aged and older Chinese adults
title_sort associations between physical activity and heart disease among middle aged and older chinese adults
topic physical activity
heart disease
middle-aged and older individuals
dose-response relationship
intensity
url https://www.frontiersin.org/articles/10.3389/fcvm.2025.1383888/full
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