Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes

Various unsaturated natural terpenes were selectively converted to the corresponding polychlorinated products in good yields using iron acetylacetonate in combination with nucleophilic cocatalyst. The synthesized compounds were evaluated for their in vitro antifungal activity. The antifungal bioassa...

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Main Authors: Hana Ighachane, Brahim Boualy, Mustapha Ait Ali, My. H. Sedra, Larbi El Firdoussi, Hassan Bihi Lazrek
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2017/2784303
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author Hana Ighachane
Brahim Boualy
Mustapha Ait Ali
My. H. Sedra
Larbi El Firdoussi
Hassan Bihi Lazrek
author_facet Hana Ighachane
Brahim Boualy
Mustapha Ait Ali
My. H. Sedra
Larbi El Firdoussi
Hassan Bihi Lazrek
author_sort Hana Ighachane
collection DOAJ
description Various unsaturated natural terpenes were selectively converted to the corresponding polychlorinated products in good yields using iron acetylacetonate in combination with nucleophilic cocatalyst. The synthesized compounds were evaluated for their in vitro antifungal activity. The antifungal bioassays showed that 2c and 2d possessed significant antifungal activity against Fusarium oxysporum f. sp. albedinis (Foa), Fusarium oxysporum f. sp. canariensis (Foc), and Verticillium dahliae (Vd).
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institution Kabale University
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publishDate 2017-01-01
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series Advances in Materials Science and Engineering
spelling doaj-art-4b03f17e271a456685b396b257d86b3d2025-02-03T06:00:44ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422017-01-01201710.1155/2017/27843032784303Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural TerpenesHana Ighachane0Brahim Boualy1Mustapha Ait Ali2My. H. Sedra3Larbi El Firdoussi4Hassan Bihi Lazrek5Laboratory of Biomolecular and Medicinal Chemistry, URAC 16, Faculty of Sciences Semlalia, Marrakech, MoroccoLaboratoire de Chimie et Modélisation Mathématique, Faculté Polydisciplinaire de Khouribga, Université Hassan 1er, BP 145, 25000 Khouribga, MoroccoEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, BP 2390, 40001 Marrakech, MoroccoLaboratory of Biomolecular and Medicinal Chemistry, URAC 16, Faculty of Sciences Semlalia, Marrakech, MoroccoEquipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, BP 2390, 40001 Marrakech, MoroccoLaboratory of Biomolecular and Medicinal Chemistry, URAC 16, Faculty of Sciences Semlalia, Marrakech, MoroccoVarious unsaturated natural terpenes were selectively converted to the corresponding polychlorinated products in good yields using iron acetylacetonate in combination with nucleophilic cocatalyst. The synthesized compounds were evaluated for their in vitro antifungal activity. The antifungal bioassays showed that 2c and 2d possessed significant antifungal activity against Fusarium oxysporum f. sp. albedinis (Foa), Fusarium oxysporum f. sp. canariensis (Foc), and Verticillium dahliae (Vd).http://dx.doi.org/10.1155/2017/2784303
spellingShingle Hana Ighachane
Brahim Boualy
Mustapha Ait Ali
My. H. Sedra
Larbi El Firdoussi
Hassan Bihi Lazrek
Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
Advances in Materials Science and Engineering
title Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
title_full Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
title_fullStr Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
title_full_unstemmed Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
title_short Catalytic Synthesis and Antifungal Activity of New Polychlorinated Natural Terpenes
title_sort catalytic synthesis and antifungal activity of new polychlorinated natural terpenes
url http://dx.doi.org/10.1155/2017/2784303
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