Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review

Designing and manufacturing devices at the micro- and nanoscales offers significant advantages, including high precision, quick response times, high energy density ratios, and low production costs. These benefits have driven extensive research in micro-electromechanical systems (MEMS) and nano-elect...

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Main Authors: Lowell Welburn, Amir Milad Moshref Javadi, Luong Nguyen, Salil Desai
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/15/6/898
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author Lowell Welburn
Amir Milad Moshref Javadi
Luong Nguyen
Salil Desai
author_facet Lowell Welburn
Amir Milad Moshref Javadi
Luong Nguyen
Salil Desai
author_sort Lowell Welburn
collection DOAJ
description Designing and manufacturing devices at the micro- and nanoscales offers significant advantages, including high precision, quick response times, high energy density ratios, and low production costs. These benefits have driven extensive research in micro-electromechanical systems (MEMS) and nano-electromechanical systems (NEMS), resulting in various classifications of materials and manufacturing techniques, which are ultimately used to produce different classifications of MEMS devices. The current work aims to systematically organize the literature on MEMS in biomedical devices, encompassing past achievements, present developments, and future prospects. This paper reviews the current research trends, highlighting significant material advancements and emerging technologies in biomedical MEMS in order to meet the current challenges facing the field, such as ensuring biocompatibility, achieving miniaturization, and maintaining precise control in biological environments. It also explores projected applications, including use in advanced diagnostic tools, targeted drug delivery systems, and innovative therapeutic devices. By mapping out these trends and prospects, this review will help identify current research gaps in the biomedical MEMS field. By pinpointing these gaps, researchers can focus on addressing unmet needs and advancing state-of-the-art biomedical MEMS technology. Ultimately, this can lead to the development of more effective and innovative biomedical devices, improving patient care and outcomes.
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series Biomolecules
spelling doaj-art-4af9d16e9d834c3890bacdf50c266cb32025-08-20T02:24:33ZengMDPI AGBiomolecules2218-273X2025-06-0115689810.3390/biom15060898Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A ReviewLowell Welburn0Amir Milad Moshref Javadi1Luong Nguyen2Salil Desai3Department of Mechanical Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USADepartment of Industrial and Systems Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USADepartment of Industrial and Systems Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USADepartment of Industrial and Systems Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USADesigning and manufacturing devices at the micro- and nanoscales offers significant advantages, including high precision, quick response times, high energy density ratios, and low production costs. These benefits have driven extensive research in micro-electromechanical systems (MEMS) and nano-electromechanical systems (NEMS), resulting in various classifications of materials and manufacturing techniques, which are ultimately used to produce different classifications of MEMS devices. The current work aims to systematically organize the literature on MEMS in biomedical devices, encompassing past achievements, present developments, and future prospects. This paper reviews the current research trends, highlighting significant material advancements and emerging technologies in biomedical MEMS in order to meet the current challenges facing the field, such as ensuring biocompatibility, achieving miniaturization, and maintaining precise control in biological environments. It also explores projected applications, including use in advanced diagnostic tools, targeted drug delivery systems, and innovative therapeutic devices. By mapping out these trends and prospects, this review will help identify current research gaps in the biomedical MEMS field. By pinpointing these gaps, researchers can focus on addressing unmet needs and advancing state-of-the-art biomedical MEMS technology. Ultimately, this can lead to the development of more effective and innovative biomedical devices, improving patient care and outcomes.https://www.mdpi.com/2218-273X/15/6/898MEMSNEMSBioMEMSbiomedicalnanotechnologybiosensor
spellingShingle Lowell Welburn
Amir Milad Moshref Javadi
Luong Nguyen
Salil Desai
Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
Biomolecules
MEMS
NEMS
BioMEMS
biomedical
nanotechnology
biosensor
title Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
title_full Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
title_fullStr Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
title_full_unstemmed Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
title_short Prospects and Trends in Biomedical Microelectromechanical Systems (MEMS) Devices: A Review
title_sort prospects and trends in biomedical microelectromechanical systems mems devices a review
topic MEMS
NEMS
BioMEMS
biomedical
nanotechnology
biosensor
url https://www.mdpi.com/2218-273X/15/6/898
work_keys_str_mv AT lowellwelburn prospectsandtrendsinbiomedicalmicroelectromechanicalsystemsmemsdevicesareview
AT amirmiladmoshrefjavadi prospectsandtrendsinbiomedicalmicroelectromechanicalsystemsmemsdevicesareview
AT luongnguyen prospectsandtrendsinbiomedicalmicroelectromechanicalsystemsmemsdevicesareview
AT salildesai prospectsandtrendsinbiomedicalmicroelectromechanicalsystemsmemsdevicesareview