Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels

This study represents a new design for an empathetic surface plasmon resonance (SPR) sensor that utilizes BlueP/TMDCs and BaTiO3 (barium titanate) and employs the angular interrogation technique to measure the glucose concentration level in urine samples. This design optimization involved extensive...

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Main Authors: Momen Sahriar Shoshi, Md Abu Huraiya, Vinoth Raj R, Abror Jawad, Chang Yi Kong, Hitoshi Tabata, Sankar Ganesh Ramaraj, S.M. Abdur Razzak
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Talanta Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666831925000049
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author Momen Sahriar Shoshi
Md Abu Huraiya
Vinoth Raj R
Abror Jawad
Chang Yi Kong
Hitoshi Tabata
Sankar Ganesh Ramaraj
S.M. Abdur Razzak
author_facet Momen Sahriar Shoshi
Md Abu Huraiya
Vinoth Raj R
Abror Jawad
Chang Yi Kong
Hitoshi Tabata
Sankar Ganesh Ramaraj
S.M. Abdur Razzak
author_sort Momen Sahriar Shoshi
collection DOAJ
description This study represents a new design for an empathetic surface plasmon resonance (SPR) sensor that utilizes BlueP/TMDCs and BaTiO3 (barium titanate) and employs the angular interrogation technique to measure the glucose concentration level in urine samples. This design optimization involved extensive numerical analysis through the use of the Transfer Matrix Method (TMM) at a visible wavelength of λ=633 nm to enhance sensitivity, full width half maximum (FWHM), detection accuracy (DA), and quality factor (QF). Additionally, Finite Element Method (FEM) analysis was used to ensure the accuracy of the findings achieved through Transfer Matrix Method (TMM). The suggested biosensor configuration involves five layers: a BK-7 glass prism, 56 nm Ag layer, 11 nm BaTiO3 layer, BlueP/TMDCs with thickness of 0.68 nm, and a sensing medium (urine sample). Unlike earlier designs relying on conventional 2D materials or single dielectric layers, the proposed hybrid structure not only enhances light-matter interaction and optimizes electromagnetic field distribution but also outperforms other hybrid sensors by achieving superior sensitivity, detection accuracy, and quality factor. Through the use of novel combination of BlueP/TMDCs and BaTiO₃ in this hybrid sensor, the biosensor achieved significantly improved performance, with enhanced sensitivity of 435 deg/RIU at a concentration of glucose 10 g/dL, QF of 86.29442 RIU−1 as well as DA of 0.190114 deg−1 spanning a refractive index (RI) from 1.335 to 1.347.
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spelling doaj-art-4af2ef574fb940a98de6264615c2f98c2025-01-12T05:26:10ZengElsevierTalanta Open2666-83192025-08-0111100401Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levelsMomen Sahriar Shoshi0Md Abu Huraiya1Vinoth Raj R2Abror Jawad3Chang Yi Kong4Hitoshi Tabata5Sankar Ganesh Ramaraj6S.M. Abdur Razzak7Department of Electrical and Electronic Engineering, Rajshahi University of Engineering & Technology, Rajshahi, 6204, BangladeshDepartment of Electrical and Electronic Engineering, Rajshahi University of Engineering & Technology, Rajshahi, 6204, BangladeshDepartment of Electronics and Communication Engineering, Saveetha Engineering College, Thandalam, Chennai,602105, Tamilnadu, IndiaDepartment of Electrical and Electronic Engineering, Rajshahi University of Engineering & Technology, Rajshahi, 6204, BangladeshDepartment of Environment and Energy System, Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku Chuo-ku, Hamamatsu 432-8561, Japan; Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku Chuo-ku, Hamamatsu 432-8561, JapanDepartment of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, JapanDepartment of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan; Corresponding authors.Department of Electrical and Electronic Engineering, Rajshahi University of Engineering & Technology, Rajshahi, 6204, Bangladesh; Corresponding authors.This study represents a new design for an empathetic surface plasmon resonance (SPR) sensor that utilizes BlueP/TMDCs and BaTiO3 (barium titanate) and employs the angular interrogation technique to measure the glucose concentration level in urine samples. This design optimization involved extensive numerical analysis through the use of the Transfer Matrix Method (TMM) at a visible wavelength of λ=633 nm to enhance sensitivity, full width half maximum (FWHM), detection accuracy (DA), and quality factor (QF). Additionally, Finite Element Method (FEM) analysis was used to ensure the accuracy of the findings achieved through Transfer Matrix Method (TMM). The suggested biosensor configuration involves five layers: a BK-7 glass prism, 56 nm Ag layer, 11 nm BaTiO3 layer, BlueP/TMDCs with thickness of 0.68 nm, and a sensing medium (urine sample). Unlike earlier designs relying on conventional 2D materials or single dielectric layers, the proposed hybrid structure not only enhances light-matter interaction and optimizes electromagnetic field distribution but also outperforms other hybrid sensors by achieving superior sensitivity, detection accuracy, and quality factor. Through the use of novel combination of BlueP/TMDCs and BaTiO₃ in this hybrid sensor, the biosensor achieved significantly improved performance, with enhanced sensitivity of 435 deg/RIU at a concentration of glucose 10 g/dL, QF of 86.29442 RIU−1 as well as DA of 0.190114 deg−1 spanning a refractive index (RI) from 1.335 to 1.347.http://www.sciencedirect.com/science/article/pii/S2666831925000049Surface plasmon resonance (SPR)Glucose detectionTransition metal dichalcogenides (TMDCs)SensitivityTransfer matrix method (TMM)Finite element method (FEM)
spellingShingle Momen Sahriar Shoshi
Md Abu Huraiya
Vinoth Raj R
Abror Jawad
Chang Yi Kong
Hitoshi Tabata
Sankar Ganesh Ramaraj
S.M. Abdur Razzak
Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
Talanta Open
Surface plasmon resonance (SPR)
Glucose detection
Transition metal dichalcogenides (TMDCs)
Sensitivity
Transfer matrix method (TMM)
Finite element method (FEM)
title Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
title_full Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
title_fullStr Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
title_full_unstemmed Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
title_short Revolutionary barium titanate-BlueP/TMDCs SPR sensor: Ultra-sensitive detection of urine glucose levels
title_sort revolutionary barium titanate bluep tmdcs spr sensor ultra sensitive detection of urine glucose levels
topic Surface plasmon resonance (SPR)
Glucose detection
Transition metal dichalcogenides (TMDCs)
Sensitivity
Transfer matrix method (TMM)
Finite element method (FEM)
url http://www.sciencedirect.com/science/article/pii/S2666831925000049
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