The ‘Mystery’ of Opioid-Induced Diarrhea
Bowel dysfunction, mainly constipation, is a well-known and anticipated side effect of opioids. The physician prescribing an opioid frequently confronts the challenge of preventing and treating bowel dysfunction. Different strategies have emerged for managing opioid-induced constipation. These strat...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2011/309685 |
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| _version_ | 1850109473709883392 |
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| author | Silviu Bril Yoav Shoham Jeremy Marcus |
| author_facet | Silviu Bril Yoav Shoham Jeremy Marcus |
| author_sort | Silviu Bril |
| collection | DOAJ |
| description | Bowel dysfunction, mainly constipation, is a well-known and anticipated side effect of opioids. The physician prescribing an opioid frequently confronts the challenge of preventing and treating bowel dysfunction. Different strategies have emerged for managing opioid-induced constipation. These strategies include physical activity, maintaining adequate fluid intake, adhering to regular daily bowel habits, using laxatives and other anticonstipation medications and, recently, using a peripheral opioid antagonist, either as a separate drug or in the form of an opioid agonist-antagonist combination pill. What options exist for the physician when a patient receiving opioids complains of diarrhea, cramps and bloating, rather than the expected constipation? The present article describes a possible cause of opioid-induced diarrhea and strategies for management. |
| format | Article |
| id | doaj-art-4ace33c91dd94db981315da2e2f74b0e |
| institution | OA Journals |
| issn | 1203-6765 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-4ace33c91dd94db981315da2e2f74b0e2025-08-20T02:38:03ZengWileyPain Research and Management1203-67652011-01-0116319719910.1155/2011/309685The ‘Mystery’ of Opioid-Induced DiarrheaSilviu Bril0Yoav Shoham1Jeremy Marcus2Center for Pain Medicine, Sourasky Medical Center, Tel Aviv, IsraelCenter for Pain Medicine, Sourasky Medical Center, Tel Aviv, IsraelWashington Nephrology Associates, Washington, DC, USABowel dysfunction, mainly constipation, is a well-known and anticipated side effect of opioids. The physician prescribing an opioid frequently confronts the challenge of preventing and treating bowel dysfunction. Different strategies have emerged for managing opioid-induced constipation. These strategies include physical activity, maintaining adequate fluid intake, adhering to regular daily bowel habits, using laxatives and other anticonstipation medications and, recently, using a peripheral opioid antagonist, either as a separate drug or in the form of an opioid agonist-antagonist combination pill. What options exist for the physician when a patient receiving opioids complains of diarrhea, cramps and bloating, rather than the expected constipation? The present article describes a possible cause of opioid-induced diarrhea and strategies for management.http://dx.doi.org/10.1155/2011/309685 |
| spellingShingle | Silviu Bril Yoav Shoham Jeremy Marcus The ‘Mystery’ of Opioid-Induced Diarrhea Pain Research and Management |
| title | The ‘Mystery’ of Opioid-Induced Diarrhea |
| title_full | The ‘Mystery’ of Opioid-Induced Diarrhea |
| title_fullStr | The ‘Mystery’ of Opioid-Induced Diarrhea |
| title_full_unstemmed | The ‘Mystery’ of Opioid-Induced Diarrhea |
| title_short | The ‘Mystery’ of Opioid-Induced Diarrhea |
| title_sort | mystery of opioid induced diarrhea |
| url | http://dx.doi.org/10.1155/2011/309685 |
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