A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature
Rhabdomyosarcoma is a rare soft tissue malignant neoplasm with striated muscle differentiation often found in the head and neck region. In our case a 33-year-old man presented with a bulging mass near his right mandibular second molar tooth, identified as a unilocular destructive lesion on an X-ray...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2025-01-01
|
| Series: | Frontiers in Dentistry |
| Subjects: | |
| Online Access: | https://fid.tums.ac.ir/index.php/fid/article/view/4462 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823863910219907072 |
|---|---|
| author | Shabnam Mashhadi Ata Garajei Pouyan Aminishakibb |
| author_facet | Shabnam Mashhadi Ata Garajei Pouyan Aminishakibb |
| author_sort | Shabnam Mashhadi |
| collection | DOAJ |
| description |
Rhabdomyosarcoma is a rare soft tissue malignant neoplasm with striated muscle differentiation often found in the head and neck region. In our case a 33-year-old man presented with a bulging mass near his right mandibular second molar tooth, identified as a unilocular destructive lesion on an X-ray. An incisional biopsy confirmed rhabdomyosarcoma, leading to a hemi-mandibulectomy. Histopathologic findings showed spindle and rhabdoid cells with positive immunoreactivity to Desmin, myogenin and myoD1. In conclusion, it is crucial to differentiate rhabdomyosarcoma from other more common intraosseous malignancies, and using Desmin staining as part of the initial immunohistochemical panel can aid in the diagnosis process.
|
| format | Article |
| id | doaj-art-4acc12919fd44c89889cfc6c455af81b |
| institution | Kabale University |
| issn | 2676-296X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Frontiers in Dentistry |
| spelling | doaj-art-4acc12919fd44c89889cfc6c455af81b2025-02-09T08:59:13ZengTehran University of Medical SciencesFrontiers in Dentistry2676-296X2025-01-012210.18502/fid.v22i4.17543A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of LiteratureShabnam Mashhadi0Ata Garajei1Pouyan Aminishakibb2Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Head and Neck Surgical Oncology and Reconstructive Surgery, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran 2.Oral and Maxillofacial Pathology Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Rhabdomyosarcoma is a rare soft tissue malignant neoplasm with striated muscle differentiation often found in the head and neck region. In our case a 33-year-old man presented with a bulging mass near his right mandibular second molar tooth, identified as a unilocular destructive lesion on an X-ray. An incisional biopsy confirmed rhabdomyosarcoma, leading to a hemi-mandibulectomy. Histopathologic findings showed spindle and rhabdoid cells with positive immunoreactivity to Desmin, myogenin and myoD1. In conclusion, it is crucial to differentiate rhabdomyosarcoma from other more common intraosseous malignancies, and using Desmin staining as part of the initial immunohistochemical panel can aid in the diagnosis process. https://fid.tums.ac.ir/index.php/fid/article/view/4462RhabdomyosarcomaMandible; Neoplasm |
| spellingShingle | Shabnam Mashhadi Ata Garajei Pouyan Aminishakibb A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature Frontiers in Dentistry Rhabdomyosarcoma Mandible; Neoplasm |
| title | A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature |
| title_full | A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature |
| title_fullStr | A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature |
| title_full_unstemmed | A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature |
| title_short | A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature |
| title_sort | primary intraosseous rhabdomyosarcoma of mandible report of a rare case and review of literature |
| topic | Rhabdomyosarcoma Mandible; Neoplasm |
| url | https://fid.tums.ac.ir/index.php/fid/article/view/4462 |
| work_keys_str_mv | AT shabnammashhadi aprimaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature AT atagarajei aprimaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature AT pouyanaminishakibb aprimaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature AT shabnammashhadi primaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature AT atagarajei primaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature AT pouyanaminishakibb primaryintraosseousrhabdomyosarcomaofmandiblereportofararecaseandreviewofliterature |