A Primary Intraosseous Rhabdomyosarcoma of Mandible: Report of a Rare Case and Review of Literature
Rhabdomyosarcoma is a rare soft tissue malignant neoplasm with striated muscle differentiation often found in the head and neck region. In our case a 33-year-old man presented with a bulging mass near his right mandibular second molar tooth, identified as a unilocular destructive lesion on an X-ray...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2025-01-01
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| Series: | Frontiers in Dentistry |
| Subjects: | |
| Online Access: | https://fid.tums.ac.ir/index.php/fid/article/view/4462 |
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| Summary: | Rhabdomyosarcoma is a rare soft tissue malignant neoplasm with striated muscle differentiation often found in the head and neck region. In our case a 33-year-old man presented with a bulging mass near his right mandibular second molar tooth, identified as a unilocular destructive lesion on an X-ray. An incisional biopsy confirmed rhabdomyosarcoma, leading to a hemi-mandibulectomy. Histopathologic findings showed spindle and rhabdoid cells with positive immunoreactivity to Desmin, myogenin and myoD1. In conclusion, it is crucial to differentiate rhabdomyosarcoma from other more common intraosseous malignancies, and using Desmin staining as part of the initial immunohistochemical panel can aid in the diagnosis process.
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| ISSN: | 2676-296X |