Correlation and prognosis analysis of human papillomavirus infection and P16 expression in oral and oropharyngeal squamous cell carcinomas

Correlation and prognosis analysis of human papillomavirus infection and P16 expression in oral and oropharyngeal squamous cell carcinomas

Abstract The incidence of HPV-related oral squamous cell carcinomas (OSCC)and oropharyngeal squamous cell carcinomas (OPSCC) has increased significantly in recent years, but the role of HPV and P16 in OSCC and OPSCC remains controversial. Here, we evaluate the prevalence and prognostic significance...

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Bibliographic Details
Main Authors: Yandie Lin, Zhirui Li, Kai Zhang, Xiaoyue Li, Liwei Shao, Aijun Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
OPSCC
OSCC
HPV DNA
HPV E6E7
P16
Prognosis
Online Access:https://doi.org/10.1038/s41598-025-95643-1
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