Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin
Aim: The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)2], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibio...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_18_25 |
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| author | Noor AlSahwan Shibu T. Mathew |
| author_facet | Noor AlSahwan Shibu T. Mathew |
| author_sort | Noor AlSahwan |
| collection | DOAJ |
| description | Aim:
The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)2], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibiotic paste [mTAP], for 3 and 6 weeks and identify the failure modes related to each medicament.
Materials and Methods:
Eighty extracted mandibular premolars were decoronated and instrumented to size 30 (Protaper Universal F3). Peeso reamers #1–#6, followed by 2.5% NaOCl, 17% EDTA, and distilled water for irrigation, were applied in sequence. The specimens were divided into four groups with n = 20/group: Group 1, Ca(OH)2; Group 2, Ca(OH)2 + CHX; Group 3, DAP; and Group 4, mTAP. The medicaments were deposited using a Lentulo spiral, and the samples were kept in saline at both 3 and 6 weeks.
Results:
MTA dislocation resistance significantly decreased with time, i.e., between 3 weeks and 6 weeks (P < 0.05). There was no significant difference at 3 weeks between Ca(OH)2 and Ca(OH)2 + CHX (P = 0.791) or at 6 weeks between Ca(OH)2 and mTAP (P = 1.000). Calcium hydroxide provided the highest bonding strength, while DAP had the lowest at both time points.
Conclusion:
The highest bond strength was shown by calcium hydroxide at both 3 and 6 weeks, while the lowest bond strength was obtained with DAP. |
| format | Article |
| id | doaj-art-4ac5ef23fc9e4676bbb8ebdc09b885e3 |
| institution | DOAJ |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-4ac5ef23fc9e4676bbb8ebdc09b885e32025-08-20T03:15:19ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-06-0117Suppl 2S1481S148310.4103/jpbs.jpbs_18_25Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to DentinNoor AlSahwanShibu T. MathewAim: The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)2], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibiotic paste [mTAP], for 3 and 6 weeks and identify the failure modes related to each medicament. Materials and Methods: Eighty extracted mandibular premolars were decoronated and instrumented to size 30 (Protaper Universal F3). Peeso reamers #1–#6, followed by 2.5% NaOCl, 17% EDTA, and distilled water for irrigation, were applied in sequence. The specimens were divided into four groups with n = 20/group: Group 1, Ca(OH)2; Group 2, Ca(OH)2 + CHX; Group 3, DAP; and Group 4, mTAP. The medicaments were deposited using a Lentulo spiral, and the samples were kept in saline at both 3 and 6 weeks. Results: MTA dislocation resistance significantly decreased with time, i.e., between 3 weeks and 6 weeks (P < 0.05). There was no significant difference at 3 weeks between Ca(OH)2 and Ca(OH)2 + CHX (P = 0.791) or at 6 weeks between Ca(OH)2 and mTAP (P = 1.000). Calcium hydroxide provided the highest bonding strength, while DAP had the lowest at both time points. Conclusion: The highest bond strength was shown by calcium hydroxide at both 3 and 6 weeks, while the lowest bond strength was obtained with DAP.https://journals.lww.com/10.4103/jpbs.jpbs_18_25antibiotic pastesdislocation resistanceintracanal medicamentsmta |
| spellingShingle | Noor AlSahwan Shibu T. Mathew Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin Journal of Pharmacy and Bioallied Sciences antibiotic pastes dislocation resistance intracanal medicaments mta |
| title | Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin |
| title_full | Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin |
| title_fullStr | Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin |
| title_full_unstemmed | Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin |
| title_short | Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin |
| title_sort | effect of medicaments used in endodontic regeneration on the dislocation resistance of mta to dentin |
| topic | antibiotic pastes dislocation resistance intracanal medicaments mta |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_18_25 |
| work_keys_str_mv | AT nooralsahwan effectofmedicamentsusedinendodonticregenerationonthedislocationresistanceofmtatodentin AT shibutmathew effectofmedicamentsusedinendodonticregenerationonthedislocationresistanceofmtatodentin |