Effect of Medicaments Used in Endodontic Regeneration on the Dislocation Resistance of MTA to Dentin
Aim: The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)2], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibio...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_18_25 |
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| Summary: | Aim:
The purpose of this study was to assess the push-out bond strength of mineral trioxide aggregate (MTA) to dentin after the use of intracanal medicaments, including calcium hydroxide [Ca(OH)2], calcium hydroxide with chlorhexidine [CHX], double antibiotic paste [DAP], and modified triple antibiotic paste [mTAP], for 3 and 6 weeks and identify the failure modes related to each medicament.
Materials and Methods:
Eighty extracted mandibular premolars were decoronated and instrumented to size 30 (Protaper Universal F3). Peeso reamers #1–#6, followed by 2.5% NaOCl, 17% EDTA, and distilled water for irrigation, were applied in sequence. The specimens were divided into four groups with n = 20/group: Group 1, Ca(OH)2; Group 2, Ca(OH)2 + CHX; Group 3, DAP; and Group 4, mTAP. The medicaments were deposited using a Lentulo spiral, and the samples were kept in saline at both 3 and 6 weeks.
Results:
MTA dislocation resistance significantly decreased with time, i.e., between 3 weeks and 6 weeks (P < 0.05). There was no significant difference at 3 weeks between Ca(OH)2 and Ca(OH)2 + CHX (P = 0.791) or at 6 weeks between Ca(OH)2 and mTAP (P = 1.000). Calcium hydroxide provided the highest bonding strength, while DAP had the lowest at both time points.
Conclusion:
The highest bond strength was shown by calcium hydroxide at both 3 and 6 weeks, while the lowest bond strength was obtained with DAP. |
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| ISSN: | 0976-4879 0975-7406 |