Ursolic acid induces apoptosis and disrupts host-parasite interactions in Theileria annulata-infected cells

Ursolic acid induces apoptosis and disrupts host-parasite interactions in Theileria annulata-infected cells

This study explores the anti-proliferative and anti-parasitic properties of ursolic acid (UA) in Theileria annulata-infected bovine (TA) cells. Dose-response analyses determined an IC50 value of approximately 5 μg/mL for UA, demonstrating selective cytotoxicity toward infected cells with minimal imp...

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Bibliographic Details
Main Authors:	Sakshi Singh, Madhusmita Subudhi, Vengatachala Moorthy A, Akash Suresh, Paresh Sharma
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Series:	International Journal for Parasitology: Drugs and Drug Resistance
Subjects:	Ursolic acid Apoptosis Apicomplexan Theileria Phosphorylation Heterochromatin
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211320725000168
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