Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application

Rational bio-organic fertilizer application has important advantages in reducing chemical fertilizer application, mitigating environmental pollution risks and enhancing plant health. However, the interplay between rhizosphere soil microbial communities, associated metabolites and the inhibiting path...

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Main Authors: Xiaoting Li, Shunping Yu, Shiqing Zhang, Yubin Xiong, Fangfang Zhou, Li Tang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biological Control
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Online Access:http://www.sciencedirect.com/science/article/pii/S1049964425000842
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author Xiaoting Li
Shunping Yu
Shiqing Zhang
Yubin Xiong
Fangfang Zhou
Li Tang
author_facet Xiaoting Li
Shunping Yu
Shiqing Zhang
Yubin Xiong
Fangfang Zhou
Li Tang
author_sort Xiaoting Li
collection DOAJ
description Rational bio-organic fertilizer application has important advantages in reducing chemical fertilizer application, mitigating environmental pollution risks and enhancing plant health. However, the interplay between rhizosphere soil microbial communities, associated metabolites and the inhibiting pathogenic bacteria mechanisms is required, particularly in the long-term bio-organic fertilizer application. Therefore, our study encompassed three experimental conditions: conventional chemical fertilizer application (CF), 20 % reduction in chemical fertilizer supplemented with organic fertilizer (OF) and 20 % chemical fertilizer reduction supplemented with bio-organic fertilizer (BOF). By integrating microbiology and metabonomics, we aimed to elucidate the effects of long-term different fertilizer measures on the rhizosphere soil microbial community and metabolic function. Compared with CF, the relative abundance of Phytophthora nicotianae in rhizosphere soil and corresponding disease significantly decreased with BOF. However, there were significant increases in the concentrations of nitrate nitrogen, total nitrogen, available phosphorus, organic matter and urease activity. Simultaneously, the relative abundance of Proteobacteria at the phylum level notably increased with BOF, whereas the relative abundance of Gemmatimonas and Sphingomonas at the genus level exhibited significant increases. Moreover, the BOF affected the complexity and stability of the soil bacterial symbiotic networks. Furthermore, the metabolite profiles were significantly altered, with the differential metabolites in KEGG metabolic pathways being notably enriched for BOF treatment, particularly in pathways related to gibberellin secondary metabolite, histidine, and tryptophan metabolism. The correlation analysis and structural equation modeling revealed significant interactions between soil properties, microorganisms and metabolites, all of which had a substantial impact on the disease incidence. Consequently, we observed that soil fertility, rhizosphere microorganisms and tryptophan metabolites collectively facilitated the favorable response of crop health to the partial replacement of chemical fertilizers with bio-organic alternatives. These findings provided novel insights into sustainable practices of the reduction of chemical fertilizer and environmental pollution.
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spelling doaj-art-4abec5ff93ee497d87839298608a1dcd2025-08-20T03:48:50ZengElsevierBiological Control1049-96442025-06-0120510577410.1016/j.biocontrol.2025.105774Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer applicationXiaoting Li0Shunping Yu1Shiqing Zhang2Yubin Xiong3Fangfang Zhou4Li Tang5College of Plant Protection, Yunnan Agricultural University, Kunming 650201, ChinaCollege of Resources and Environmental Science, Yunnan Agricultural University, Kunming 650201, ChinaCollege of Resources and Environmental Science, Yunnan Agricultural University, Kunming 650201, ChinaCollege of Resources and Environmental Science, Yunnan Agricultural University, Kunming 650201, ChinaCollege of Plant Protection, Yunnan Agricultural University, Kunming 650201, ChinaCollege of Plant Protection, Yunnan Agricultural University, Kunming 650201, China; College of Resources and Environmental Science, Yunnan Agricultural University, Kunming 650201, China; Corresponding author at: College of Plant Protection and College of Resources and Environmental Science, Yunnan Agricultural University, Kunming 650201, China.Rational bio-organic fertilizer application has important advantages in reducing chemical fertilizer application, mitigating environmental pollution risks and enhancing plant health. However, the interplay between rhizosphere soil microbial communities, associated metabolites and the inhibiting pathogenic bacteria mechanisms is required, particularly in the long-term bio-organic fertilizer application. Therefore, our study encompassed three experimental conditions: conventional chemical fertilizer application (CF), 20 % reduction in chemical fertilizer supplemented with organic fertilizer (OF) and 20 % chemical fertilizer reduction supplemented with bio-organic fertilizer (BOF). By integrating microbiology and metabonomics, we aimed to elucidate the effects of long-term different fertilizer measures on the rhizosphere soil microbial community and metabolic function. Compared with CF, the relative abundance of Phytophthora nicotianae in rhizosphere soil and corresponding disease significantly decreased with BOF. However, there were significant increases in the concentrations of nitrate nitrogen, total nitrogen, available phosphorus, organic matter and urease activity. Simultaneously, the relative abundance of Proteobacteria at the phylum level notably increased with BOF, whereas the relative abundance of Gemmatimonas and Sphingomonas at the genus level exhibited significant increases. Moreover, the BOF affected the complexity and stability of the soil bacterial symbiotic networks. Furthermore, the metabolite profiles were significantly altered, with the differential metabolites in KEGG metabolic pathways being notably enriched for BOF treatment, particularly in pathways related to gibberellin secondary metabolite, histidine, and tryptophan metabolism. The correlation analysis and structural equation modeling revealed significant interactions between soil properties, microorganisms and metabolites, all of which had a substantial impact on the disease incidence. Consequently, we observed that soil fertility, rhizosphere microorganisms and tryptophan metabolites collectively facilitated the favorable response of crop health to the partial replacement of chemical fertilizers with bio-organic alternatives. These findings provided novel insights into sustainable practices of the reduction of chemical fertilizer and environmental pollution.http://www.sciencedirect.com/science/article/pii/S1049964425000842Bio-organic fertilizerSoil microbiomeSoil metabolomePhytophthora nicotianae
spellingShingle Xiaoting Li
Shunping Yu
Shiqing Zhang
Yubin Xiong
Fangfang Zhou
Li Tang
Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
Biological Control
Bio-organic fertilizer
Soil microbiome
Soil metabolome
Phytophthora nicotianae
title Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
title_full Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
title_fullStr Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
title_full_unstemmed Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
title_short Integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting Phytophthora nicotianae under long-term bio-organic fertilizer application
title_sort integrated the rhizosphere soil microbiota and metabolome reveal mechanisms inhibiting phytophthora nicotianae under long term bio organic fertilizer application
topic Bio-organic fertilizer
Soil microbiome
Soil metabolome
Phytophthora nicotianae
url http://www.sciencedirect.com/science/article/pii/S1049964425000842
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