SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux

SIRT1-Dependent Neuroprotection by Resveratrol in TOCP-Induced Spinal Cord Injury: Modulation of ER Stress and Autophagic Flux

This study explores the neuroprotective effects of resveratrol (Resv) against tri-o-cresyl phosphate (TOCP)-induced neurotoxicity in the spinal cord of adult hens. It is well documented that TOCP exposure causes significant neurodegeneration via mechanisms that involve endoplasmic reticulum (ER) str...

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Bibliographic Details
Main Authors: Xiangsheng Tian, Yiquan Ou, Shengyuan Shi, Qiuhua Zhou, Sihong Long, Yao Xiang, Weichao Zhao, Dingxin Long
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Toxics
Subjects:
resveratrol
neurotoxicity
tri-o-cresyl phosphate
sirtuin1
endoplasmic reticulum stress
autophagy
Online Access:https://www.mdpi.com/2305-6304/12/11/810
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