Role of Toll-Like Receptor 4 on Lupus Lung Injury and Atherosclerosis in LPS-Challenge ApoE−/− Mice

Role of Toll-Like Receptor 4 on Lupus Lung Injury and Atherosclerosis in LPS-Challenge ApoE−/− Mice

To investigate the pathologic mechanisms of toll-like receptor 4 (TLR4) in lung injury and atherosclerosis, ApoE−/− or wild-type mice were intraperitoneally administered saline, lipopolysaccharides (LPS), or LPS plus TAK-242 (TLR4 inhibitor), respectively, twice a week for 4 weeks. Serum autoantibod...

Full description

Saved in:
Bibliographic Details
Main Authors: Jing-qin Ni, Qiufang Ouyang, Ling Lin, Ziyang Huang, Huixia Lu, Xiaoqing Chen, Huili Lin, Zhenhua Wang, Dongming Xu, Yun Zhang
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/476856
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items