Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study
Objective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic in...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2021/4318423 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849405893271093248 |
|---|---|
| author | Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro |
| author_facet | Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro |
| author_sort | Mônika Machado de Carvalho |
| collection | DOAJ |
| description | Objective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic indexes) and detection of human papillomavirus (nested PCR technique using PGMY 09 and 11 primers, GP+5, and GP+6) were performed. For the analysis of the results, the data were categorized into two groups: with coinfection (HIV+/HPV+) and without coinfection (HIV+/HPV–). Results. Eighty-two HIV-positive women, aged between 35 and 49 years, participated in this study among whom 50% had HPV coinfection (HIV+/HPV+). Regarding comorbidities, there was a predominance of dyslipidemia (46.3%). The analysis of laboratory determinations and atherogenic indexes showed statistical relevance in the serum concentrations of total cholesterol (p=0.04), LDL cholesterol (p=0.03), and non-HDL cholesterol (p=0.04), as well as for the Castelli I index, Castelli II index, and atherogenic coefficient (p=0.04, 0.04, and 0.03, respectively). Conclusion. The present study demonstrated a correlation between the lipid profile and atherogenic indexes with HIV/HPV coinfection, demonstrating a possible synergy between these viruses. However, further studies in this area must be carried out. |
| format | Article |
| id | doaj-art-4ab440ab09d24c8da1b4458290abe59f |
| institution | Kabale University |
| issn | 2090-908X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-4ab440ab09d24c8da1b4458290abe59f2025-08-20T03:36:34ZengWileyScientifica2090-908X2021-01-01202110.1155/2021/4318423Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary StudyMônika Machado de Carvalho0Karina Donato Fook1Maria José Abigail Mendes Araújo2Sulayne Janayna Araújo Guimarães3Camila Penha Abreu Souza4Carla Déa Trindade Barbosa5Ana Cléa Cutrim Diniz de Morais6Alessandra Costa de Sales Muniz7Deborah Rocha de Araújo8Maria Fernanda Bezerra Lima Bertolaccini9Ilka Kassandra Pereira Belfort10Marcelo de Souza Andrade11Sally Cristina Moutinho Monteiro12Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Laboratory Professional of Clinical Analysis and Histocompatibility of Universitary Hospital of Federal University of Maranhão (UFMA)Laboratory Professional of Clinical Analysis and Histocompatibility of Universitary Hospital of Federal University of Maranhão (UFMA)Laboratory Professional of Clinical Analysis and Histocompatibility of Universitary Hospital of Federal University of Maranhão (UFMA)Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Laboratory Professional of Clinical Analysis and Histocompatibility of Universitary Hospital of Federal University of Maranhão (UFMA)Postgraduate Student in Adult Health Program of Federal University of Maranhão-(UFMA) and Professional of Clinical Analysis and Histocompatibility of University Hospital of Federal University of Maranhão (UFMA)Federal University of Maranhão (UFMA)Professors of Post-Graduation Adult Health Program of Federal University of Maranhão (UFMA)Professors of Post-Graduation Adult Health Program of Federal University of Maranhão (UFMA)Objective. The present study aimed to evaluate the lipid profile and atherogenic indexes in HIV-positive women with and without coinfection with human papillomavirus. Methods. Preliminary study was conducted with HIV-positive women. Laboratory tests (lipid profile, glycid profile, and atherogenic indexes) and detection of human papillomavirus (nested PCR technique using PGMY 09 and 11 primers, GP+5, and GP+6) were performed. For the analysis of the results, the data were categorized into two groups: with coinfection (HIV+/HPV+) and without coinfection (HIV+/HPV–). Results. Eighty-two HIV-positive women, aged between 35 and 49 years, participated in this study among whom 50% had HPV coinfection (HIV+/HPV+). Regarding comorbidities, there was a predominance of dyslipidemia (46.3%). The analysis of laboratory determinations and atherogenic indexes showed statistical relevance in the serum concentrations of total cholesterol (p=0.04), LDL cholesterol (p=0.03), and non-HDL cholesterol (p=0.04), as well as for the Castelli I index, Castelli II index, and atherogenic coefficient (p=0.04, 0.04, and 0.03, respectively). Conclusion. The present study demonstrated a correlation between the lipid profile and atherogenic indexes with HIV/HPV coinfection, demonstrating a possible synergy between these viruses. However, further studies in this area must be carried out.http://dx.doi.org/10.1155/2021/4318423 |
| spellingShingle | Mônika Machado de Carvalho Karina Donato Fook Maria José Abigail Mendes Araújo Sulayne Janayna Araújo Guimarães Camila Penha Abreu Souza Carla Déa Trindade Barbosa Ana Cléa Cutrim Diniz de Morais Alessandra Costa de Sales Muniz Deborah Rocha de Araújo Maria Fernanda Bezerra Lima Bertolaccini Ilka Kassandra Pereira Belfort Marcelo de Souza Andrade Sally Cristina Moutinho Monteiro Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study Scientifica |
| title | Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_full | Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_fullStr | Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_full_unstemmed | Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_short | Prevalence of Dyslipidemia in HIV-Positive Women with HPV Coinfection: A Preliminary Study |
| title_sort | prevalence of dyslipidemia in hiv positive women with hpv coinfection a preliminary study |
| url | http://dx.doi.org/10.1155/2021/4318423 |
| work_keys_str_mv | AT monikamachadodecarvalho prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT karinadonatofook prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT mariajoseabigailmendesaraujo prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT sulaynejanaynaaraujoguimaraes prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT camilapenhaabreusouza prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT carladeatrindadebarbosa prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT anacleacutrimdinizdemorais prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT alessandracostadesalesmuniz prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT deborahrochadearaujo prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT mariafernandabezerralimabertolaccini prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT ilkakassandrapereirabelfort prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT marcelodesouzaandrade prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy AT sallycristinamoutinhomonteiro prevalenceofdyslipidemiainhivpositivewomenwithhpvcoinfectionapreliminarystudy |