Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

Simian immunodeficiency viruses (SIVs) comprise a large group of primate lentiviruses that endemically infect African monkeys. HIV-1 spilled over to humans from this viral reservoir, but the spillover did not occur directly from monkeys to humans. Instead, a key event was the introduction of SIVs in...

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Bibliographic Details
Main Authors: Cody J Warren, Arturo Barbachano-Guerrero, Vanessa L Bauer, Alex Stabell, Obaiah Dirasantha, Qing Yang, Sara L Sawyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
receptors
arms race
adaptation
Online Access:https://elifesciences.org/articles/93316
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