Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis
Abstract Background Active Facial nerve (FN) management, including decompression, end-to-end or rerouting anastomosis, and grafting consistently plays an important role in the surgical management of petrous bone cholesteatoma (PBC), and postoperative FN function is also a major concern for surgeons....
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BMC
2025-05-01
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| Series: | Head & Face Medicine |
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| Online Access: | https://doi.org/10.1186/s13005-025-00520-x |
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| author | Qin Wang Ruoya Wang Jianze Wang Na Sai Shuhang Fan Jianbin Sun Zhikai Zhao Junhui Huang Weidong Shen Weiju Han |
| author_facet | Qin Wang Ruoya Wang Jianze Wang Na Sai Shuhang Fan Jianbin Sun Zhikai Zhao Junhui Huang Weidong Shen Weiju Han |
| author_sort | Qin Wang |
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| description | Abstract Background Active Facial nerve (FN) management, including decompression, end-to-end or rerouting anastomosis, and grafting consistently plays an important role in the surgical management of petrous bone cholesteatoma (PBC), and postoperative FN function is also a major concern for surgeons. The aim of this study is to analyze the long-term FN function outcomes in PBC patients with FN paralysis who have underwent different managements and to explore the prognostic factors. Methods A retrospective analysis of 160 PBC patients with preoperative FN paralysis was conducted, and long-term FN function outcome was evaluated. Multivariate ordinal logistic regression models were used to determine the prognostic factors. Results 160 patients were collected. 102 males (63.75%) and 58 females (36.25%) with mean age 34.09 ± 13.54 years (range: 5.58-77 years). Mean FN paralysis duration preoperatively was 62.5 ± 90.80 months (range: 4 days-46 years). The preoperative/postoperative House-Brackmann (H-B) grade are as follows: H-B (I-II): 0/38 cases, H-B III: 11/37 cases, H-B IV: 22/38 cases, H-B V: 21/14 cases. H-B VI: 106/33 cases. The poorer preoperative FN function, the poorer postoperative FN function (r s =0.745, P < 0.001). Among 160 PBC patients, 127 patients underwent active FN management, 94/127 (74.0%) with preoperative H-B (V-VI) improved postoperatively. 33 patients were not eligible for FN repair, due to prolonged period of complete FN paralysis. FN decompression achieved H-B (I-II) recovery in 100% of H-B (III-IV) patients (22/22) within 12 months of paralysis and 88.9% (8/9) of H-B (V-VI) patients operated within 2 months of paralysis. End-to-end/rerouting anastomosis achieved H-B III recovery in 77.8% (14/18) of patients treated within 12 months. Greater auricular nerve graft within 12 months of paralysis achieved H-B III recovery in 75% of patients. Hypoglossal-FN anastomosis yielded H-B IV recovery in 7/12 patients (58.3%). Multivariate analysis identified worse preoperative FN function and prolonged FN paralysis duration (P < 0.05) as independent risk factors for poor prognosis. Conclusions Patients with FN paralysis can undergo active FN management to reconstruct FN function, depending on the preoperative FN function and the duration of FN paralysis. Worse preoperative FN function and longer duration of FN paralysis (P < 0.05) are risk factors for poorer prognosis. |
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| institution | DOAJ |
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| spelling | doaj-art-4aa67e8d4f3b45189a8c407b34c96ec02025-08-20T03:22:03ZengBMCHead & Face Medicine1746-160X2025-05-0121111210.1186/s13005-025-00520-xOutcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysisQin Wang0Ruoya Wang1Jianze Wang2Na Sai3Shuhang Fan4Jianbin Sun5Zhikai Zhao6Junhui Huang7Weidong Shen8Weiju Han9Senior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentDepartment of Otolaryngology, the First Affiliated Hospital of Jinzhou Medical UniversityNo.980 Hospital of PLA Joint Logistics Support ForcesSenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentSenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentThe Second Affiliated Hospital of Xi’an Jiaotong UniversitySenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentSenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentSenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentSenior Department of Otorhinolaryngology Head and Neck Surgery, The 6th Medical Center, Chinese PLA General Hospital; Medical School of Chinese PLA; State Key Laboratory of Hearing and Balance Science; National Clinical Research Center for Otorhinolaryngologic Diseases; State Key Lab of Hearing Science, Ministry of Education; Beijing Key Lab of Hearing Impairment for Prevention and TreatmentAbstract Background Active Facial nerve (FN) management, including decompression, end-to-end or rerouting anastomosis, and grafting consistently plays an important role in the surgical management of petrous bone cholesteatoma (PBC), and postoperative FN function is also a major concern for surgeons. The aim of this study is to analyze the long-term FN function outcomes in PBC patients with FN paralysis who have underwent different managements and to explore the prognostic factors. Methods A retrospective analysis of 160 PBC patients with preoperative FN paralysis was conducted, and long-term FN function outcome was evaluated. Multivariate ordinal logistic regression models were used to determine the prognostic factors. Results 160 patients were collected. 102 males (63.75%) and 58 females (36.25%) with mean age 34.09 ± 13.54 years (range: 5.58-77 years). Mean FN paralysis duration preoperatively was 62.5 ± 90.80 months (range: 4 days-46 years). The preoperative/postoperative House-Brackmann (H-B) grade are as follows: H-B (I-II): 0/38 cases, H-B III: 11/37 cases, H-B IV: 22/38 cases, H-B V: 21/14 cases. H-B VI: 106/33 cases. The poorer preoperative FN function, the poorer postoperative FN function (r s =0.745, P < 0.001). Among 160 PBC patients, 127 patients underwent active FN management, 94/127 (74.0%) with preoperative H-B (V-VI) improved postoperatively. 33 patients were not eligible for FN repair, due to prolonged period of complete FN paralysis. FN decompression achieved H-B (I-II) recovery in 100% of H-B (III-IV) patients (22/22) within 12 months of paralysis and 88.9% (8/9) of H-B (V-VI) patients operated within 2 months of paralysis. End-to-end/rerouting anastomosis achieved H-B III recovery in 77.8% (14/18) of patients treated within 12 months. Greater auricular nerve graft within 12 months of paralysis achieved H-B III recovery in 75% of patients. Hypoglossal-FN anastomosis yielded H-B IV recovery in 7/12 patients (58.3%). Multivariate analysis identified worse preoperative FN function and prolonged FN paralysis duration (P < 0.05) as independent risk factors for poor prognosis. Conclusions Patients with FN paralysis can undergo active FN management to reconstruct FN function, depending on the preoperative FN function and the duration of FN paralysis. Worse preoperative FN function and longer duration of FN paralysis (P < 0.05) are risk factors for poorer prognosis.https://doi.org/10.1186/s13005-025-00520-xPetrous bone cholesteatomaFacial nerveDecompressionAnastomosisGrafting |
| spellingShingle | Qin Wang Ruoya Wang Jianze Wang Na Sai Shuhang Fan Jianbin Sun Zhikai Zhao Junhui Huang Weidong Shen Weiju Han Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis Head & Face Medicine Petrous bone cholesteatoma Facial nerve Decompression Anastomosis Grafting |
| title | Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| title_full | Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| title_fullStr | Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| title_full_unstemmed | Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| title_short | Outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| title_sort | outcome of different facial nerve managements in petrous bone cholesteatoma patients with facial paralysis |
| topic | Petrous bone cholesteatoma Facial nerve Decompression Anastomosis Grafting |
| url | https://doi.org/10.1186/s13005-025-00520-x |
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