Evaluation of auditory system in vitiligo patients: A case-control study
Background: Vitiligo is a common acquired pigmentary disorder characterized by well-defined areas of depigmentation due to loss of melanocytes. Vitiligo can affect melanocytes in the auditory system and potentially hearing. Objective: The aim of this study was to investigate hearing changes in vitil...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-11-01
|
| Series: | Clinical Epidemiology and Global Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213398424003270 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850035907633086464 |
|---|---|
| author | Sima Tajik Kosar Nazary Azar Shirzadian Kebria Keyvan Kiakojori |
| author_facet | Sima Tajik Kosar Nazary Azar Shirzadian Kebria Keyvan Kiakojori |
| author_sort | Sima Tajik |
| collection | DOAJ |
| description | Background: Vitiligo is a common acquired pigmentary disorder characterized by well-defined areas of depigmentation due to loss of melanocytes. Vitiligo can affect melanocytes in the auditory system and potentially hearing. Objective: The aim of this study was to investigate hearing changes in vitiligo patients. Methods: Twenty-six with vitiligo patients and 26 demographically matched healthy controls were included in this study. Audiological function was evaluated using pure tone audiometry (PTA), speech audiometry and tympanometry tests in all subjects. Results: The mean hearing threshold of the left ear at frequencies of 250 and 8000 Hz in vitiligo patients was significantly higher than the control group. Sensorineural hearing loss (SNHL) was seen in 14 (53.8 %) vitiligo patients and 5(19.2 %) control group (p < 0.05). Most affected patients (10/14; 71 %) had bilateral hearing loss especially in high frequency (8000 Hz). A significant association was identified between vitiligo and SNHL (OR 4.9; 95 % CI, 1.41–16.98, P = 0.01). There was a statistically significant correlation between hearing impairment and age in both groups. Gender, severity, activity and duration of vitiligo had no a significant effect on the results of audiometric tests. Conclusion: This study confirmed that the auditory system was affected in vitiligo patients. Vitiligo patients might be at a higher risk for auditory abnormalities at a younger age than control subjects. Auditory evaluation of vitiligo patients should be considered for early detection of hearing loss. |
| format | Article |
| id | doaj-art-4aa34cc8710242e2bd5dd2e4dbf491b5 |
| institution | DOAJ |
| issn | 2213-3984 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Epidemiology and Global Health |
| spelling | doaj-art-4aa34cc8710242e2bd5dd2e4dbf491b52025-08-20T02:57:21ZengElsevierClinical Epidemiology and Global Health2213-39842024-11-013010183010.1016/j.cegh.2024.101830Evaluation of auditory system in vitiligo patients: A case-control studySima Tajik0Kosar Nazary1Azar Shirzadian Kebria2Keyvan Kiakojori3Department of Audiology, School of Rehabilitation Science, Babol University of Medical Sciences, Babol, IranStudent Research Committee, Babol University of Medical Sciences, Babol, IranClinical Research Development Unit of Yahyanejad Hospital, Babol University of Medical Sciences, Babol, Iran; Department of Dermatology, School of Medicine, Babol University of Medical Sciences, Babol, Iran; Corresponding author. Clinical Research Development Unit of Yahyanejad Hospital, Babol University of Medical Sciences, Babol, Iran.Department of Otorhinolaryngology, School of Medicine, Babol University of Medical Sciences, Babol, IranBackground: Vitiligo is a common acquired pigmentary disorder characterized by well-defined areas of depigmentation due to loss of melanocytes. Vitiligo can affect melanocytes in the auditory system and potentially hearing. Objective: The aim of this study was to investigate hearing changes in vitiligo patients. Methods: Twenty-six with vitiligo patients and 26 demographically matched healthy controls were included in this study. Audiological function was evaluated using pure tone audiometry (PTA), speech audiometry and tympanometry tests in all subjects. Results: The mean hearing threshold of the left ear at frequencies of 250 and 8000 Hz in vitiligo patients was significantly higher than the control group. Sensorineural hearing loss (SNHL) was seen in 14 (53.8 %) vitiligo patients and 5(19.2 %) control group (p < 0.05). Most affected patients (10/14; 71 %) had bilateral hearing loss especially in high frequency (8000 Hz). A significant association was identified between vitiligo and SNHL (OR 4.9; 95 % CI, 1.41–16.98, P = 0.01). There was a statistically significant correlation between hearing impairment and age in both groups. Gender, severity, activity and duration of vitiligo had no a significant effect on the results of audiometric tests. Conclusion: This study confirmed that the auditory system was affected in vitiligo patients. Vitiligo patients might be at a higher risk for auditory abnormalities at a younger age than control subjects. Auditory evaluation of vitiligo patients should be considered for early detection of hearing loss.http://www.sciencedirect.com/science/article/pii/S2213398424003270VitiligoHearing lossAuditoryMelanocyte |
| spellingShingle | Sima Tajik Kosar Nazary Azar Shirzadian Kebria Keyvan Kiakojori Evaluation of auditory system in vitiligo patients: A case-control study Clinical Epidemiology and Global Health Vitiligo Hearing loss Auditory Melanocyte |
| title | Evaluation of auditory system in vitiligo patients: A case-control study |
| title_full | Evaluation of auditory system in vitiligo patients: A case-control study |
| title_fullStr | Evaluation of auditory system in vitiligo patients: A case-control study |
| title_full_unstemmed | Evaluation of auditory system in vitiligo patients: A case-control study |
| title_short | Evaluation of auditory system in vitiligo patients: A case-control study |
| title_sort | evaluation of auditory system in vitiligo patients a case control study |
| topic | Vitiligo Hearing loss Auditory Melanocyte |
| url | http://www.sciencedirect.com/science/article/pii/S2213398424003270 |
| work_keys_str_mv | AT simatajik evaluationofauditorysysteminvitiligopatientsacasecontrolstudy AT kosarnazary evaluationofauditorysysteminvitiligopatientsacasecontrolstudy AT azarshirzadiankebria evaluationofauditorysysteminvitiligopatientsacasecontrolstudy AT keyvankiakojori evaluationofauditorysysteminvitiligopatientsacasecontrolstudy |