Health loss and economic burden of asthma in China: a qualitative review based on existing literature
Abstract Background Asthma is a significant public health issue that cannot be ignored in China and around the world, bringing a huge social burden. Objectives To evaluate the disease burden of asthma in China, including health loss and cost of illness, and identify its influencing factors. Methods...
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BMC
2025-02-01
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| Series: | Archives of Public Health |
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| Online Access: | https://doi.org/10.1186/s13690-025-01515-5 |
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| author | Peng Zhang Jiaxin Xu Baichuan Xu Yiyin Zhang Yang Xie |
| author_facet | Peng Zhang Jiaxin Xu Baichuan Xu Yiyin Zhang Yang Xie |
| author_sort | Peng Zhang |
| collection | DOAJ |
| description | Abstract Background Asthma is a significant public health issue that cannot be ignored in China and around the world, bringing a huge social burden. Objectives To evaluate the disease burden of asthma in China, including health loss and cost of illness, and identify its influencing factors. Methods A systematic literature review and qualitative descriptive analysis were conducted, Literature was accessed through PubMed, EMBASE, Web of Science, CNKI, Wangfang Data, and VIP databases, with a cutoff date of April 3, 2024. The analysis focused on two main aspects: health loss burden, measured by disability-adjusted life years (DALYs), including years of life lost (YLLs) and years lived with disability (YLDs); and economic burden, assessed through direct and indirect costs. The risk of bias in economic studies was assessed using an 11-item methodological checklist for cost of illness, while cross-sectional studies were evaluated using the Agency for Healthcare Research and Quality’s recommendation rating tool. Results The analysis included 50 studies, with eight focused on health loss and 42 on economic burden. The health loss studies showed a 51% decrease in asthma's age-standardized DALYs rate over 30 years, from 209.24 to 102.81 per 100,000 person-years. The health loss burden is influenced by factors such as high BMI, smoking, and occupational exposure. Economic burden studies reported annual direct costs from $348 to $1187 per capita, indirect costs from $7 to $1195, and hospitalization costs from $177 to $1547, influenced by frequency and severity of acute exacerbation, comorbidities, and treatment adherence. Quality assessment revealed moderate overall quality, with gaps in sensitivity analyses and cost data transparency. Conclusion The health loss burden of asthma in China has significantly decreased from 1990 to 2019, with males experiencing a higher burden. However, regional disparities in the economic burden persist, highlighting the need for improved management and adherence to standardized treatment protocols to address these disparities. |
| format | Article |
| id | doaj-art-4a8f4b2740b14315a95e76c04667f141 |
| institution | Kabale University |
| issn | 2049-3258 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Archives of Public Health |
| spelling | doaj-art-4a8f4b2740b14315a95e76c04667f1412025-02-09T12:13:46ZengBMCArchives of Public Health2049-32582025-02-0183111810.1186/s13690-025-01515-5Health loss and economic burden of asthma in China: a qualitative review based on existing literaturePeng Zhang0Jiaxin Xu1Baichuan Xu2Yiyin Zhang3Yang Xie4Department of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese MedicineDepartment of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese MedicineDepartment of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese MedicineDepartment of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese MedicineDepartment of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese MedicineAbstract Background Asthma is a significant public health issue that cannot be ignored in China and around the world, bringing a huge social burden. Objectives To evaluate the disease burden of asthma in China, including health loss and cost of illness, and identify its influencing factors. Methods A systematic literature review and qualitative descriptive analysis were conducted, Literature was accessed through PubMed, EMBASE, Web of Science, CNKI, Wangfang Data, and VIP databases, with a cutoff date of April 3, 2024. The analysis focused on two main aspects: health loss burden, measured by disability-adjusted life years (DALYs), including years of life lost (YLLs) and years lived with disability (YLDs); and economic burden, assessed through direct and indirect costs. The risk of bias in economic studies was assessed using an 11-item methodological checklist for cost of illness, while cross-sectional studies were evaluated using the Agency for Healthcare Research and Quality’s recommendation rating tool. Results The analysis included 50 studies, with eight focused on health loss and 42 on economic burden. The health loss studies showed a 51% decrease in asthma's age-standardized DALYs rate over 30 years, from 209.24 to 102.81 per 100,000 person-years. The health loss burden is influenced by factors such as high BMI, smoking, and occupational exposure. Economic burden studies reported annual direct costs from $348 to $1187 per capita, indirect costs from $7 to $1195, and hospitalization costs from $177 to $1547, influenced by frequency and severity of acute exacerbation, comorbidities, and treatment adherence. Quality assessment revealed moderate overall quality, with gaps in sensitivity analyses and cost data transparency. Conclusion The health loss burden of asthma in China has significantly decreased from 1990 to 2019, with males experiencing a higher burden. However, regional disparities in the economic burden persist, highlighting the need for improved management and adherence to standardized treatment protocols to address these disparities.https://doi.org/10.1186/s13690-025-01515-5Disease burdenEconomic burdenDALYsAsthmaSystematic review |
| spellingShingle | Peng Zhang Jiaxin Xu Baichuan Xu Yiyin Zhang Yang Xie Health loss and economic burden of asthma in China: a qualitative review based on existing literature Archives of Public Health Disease burden Economic burden DALYs Asthma Systematic review |
| title | Health loss and economic burden of asthma in China: a qualitative review based on existing literature |
| title_full | Health loss and economic burden of asthma in China: a qualitative review based on existing literature |
| title_fullStr | Health loss and economic burden of asthma in China: a qualitative review based on existing literature |
| title_full_unstemmed | Health loss and economic burden of asthma in China: a qualitative review based on existing literature |
| title_short | Health loss and economic burden of asthma in China: a qualitative review based on existing literature |
| title_sort | health loss and economic burden of asthma in china a qualitative review based on existing literature |
| topic | Disease burden Economic burden DALYs Asthma Systematic review |
| url | https://doi.org/10.1186/s13690-025-01515-5 |
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