Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature

Malignant melanoma is characterized by the ability of diffuse metastases. Since the first report of an isolated malignant melanoma case of the gallbladder, it is already controversial whether isolated cases are metastatic or primary tumors. A 49-year-old woman appealed to the emergency unit because...

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Main Authors: Mehmet Fatih Haskaraca, Mustafa Ozsoy, İsmail Özsan, Kamile Kurt
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2012/693547
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author Mehmet Fatih Haskaraca
Mustafa Ozsoy
İsmail Özsan
Kamile Kurt
author_facet Mehmet Fatih Haskaraca
Mustafa Ozsoy
İsmail Özsan
Kamile Kurt
author_sort Mehmet Fatih Haskaraca
collection DOAJ
description Malignant melanoma is characterized by the ability of diffuse metastases. Since the first report of an isolated malignant melanoma case of the gallbladder, it is already controversial whether isolated cases are metastatic or primary tumors. A 49-year-old woman appealed to the emergency unit because of abdominal pain. Ultrasonography revealed increased thickness of the gallbladder wall and a lesion with surrounding fluid sized 12 mm without acoustic shadow, which arose from the gallbladder wall and was consistent with a polyp. Histopathologic evaluation of the surgical specimen after laparoscopic cholecystectomy revealed malign epithelial tumor consisting of atypical cells with large eosinophilic cytoplasm and dense melanin pigment within the cytoplasm of the tumor cells. As no other focus was identified as a result of the evaluation, the patient was diagnosed with primary malignant melanoma of the gallbladder. In this paper, we aimed to define our treatment modality for a case with isolated malignant melanoma of the gallbladder.
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issn 2090-6900
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publishDate 2012-01-01
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series Case Reports in Surgery
spelling doaj-art-4a8df9dd73c042439f77548fc2e47f8a2025-02-03T05:51:21ZengWileyCase Reports in Surgery2090-69002090-69192012-01-01201210.1155/2012/693547693547Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the LiteratureMehmet Fatih Haskaraca0Mustafa Ozsoy1İsmail Özsan2Kamile Kurt3Department of General Surgery, Merkez Efendi State Hospital, 35630 Manisa, TurkeyDepartment of General Surgery, Merkez Efendi State Hospital, 35630 Manisa, TurkeyDepartment of General Surgery, Izmir University, Izmir, TurkeyDepartment of Pathology, Merkez Efendi State Hospital, Manisa, TurkeyMalignant melanoma is characterized by the ability of diffuse metastases. Since the first report of an isolated malignant melanoma case of the gallbladder, it is already controversial whether isolated cases are metastatic or primary tumors. A 49-year-old woman appealed to the emergency unit because of abdominal pain. Ultrasonography revealed increased thickness of the gallbladder wall and a lesion with surrounding fluid sized 12 mm without acoustic shadow, which arose from the gallbladder wall and was consistent with a polyp. Histopathologic evaluation of the surgical specimen after laparoscopic cholecystectomy revealed malign epithelial tumor consisting of atypical cells with large eosinophilic cytoplasm and dense melanin pigment within the cytoplasm of the tumor cells. As no other focus was identified as a result of the evaluation, the patient was diagnosed with primary malignant melanoma of the gallbladder. In this paper, we aimed to define our treatment modality for a case with isolated malignant melanoma of the gallbladder.http://dx.doi.org/10.1155/2012/693547
spellingShingle Mehmet Fatih Haskaraca
Mustafa Ozsoy
İsmail Özsan
Kamile Kurt
Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
Case Reports in Surgery
title Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
title_full Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
title_fullStr Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
title_full_unstemmed Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
title_short Primary Malignant Melanoma of the Gallbladder: A Case Report and Review of the Literature
title_sort primary malignant melanoma of the gallbladder a case report and review of the literature
url http://dx.doi.org/10.1155/2012/693547
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