A Formulation–Process–Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route

A Formulation–Process–Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route

<b>Background/Objectives</b>: Tablet is the most popular oral solid dosage form, and high-shear wet granulation and tableting (HSWGT) is a versatile technique for manufacturing tablets. The conventional pharmaceutical development for HSWGT is carried out in a step-by-step mode, which is...

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Bibliographic Details
Main Authors:	Zichen Liang, Xuefang Tang, Liping Chen, Yifei Liu, Shuying Zhao, Xiao Ma, Gan Luo, Bing Xu
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Series:	Pharmaceutics
Subjects:	high-shear wet granulation and tableting (HSWGT) material library quality by digital design (QbDD) formulation-process-product integrated design (FPPID) in silico simulation
Online Access:	https://www.mdpi.com/1999-4923/17/3/322
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