Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification
Abstract Background Classifying uterine fibroid using the International Federation of Gynecology and Obstetrics (FIGO) classification system assists treatment decision-making and planning. This study aimed to study whether different fibroid locations influence clinical outcomes following uterine art...
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SpringerOpen
2025-01-01
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| Series: | CVIR Endovascular |
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| Online Access: | https://doi.org/10.1186/s42155-025-00520-7 |
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| author | Yoshimi Nozaki Shiori Takeuchi Masafumi Arai Yoshiki Kuwatsuru Hiroshi Toei Shingo Okada Hitomi Kato Naoko Saito Takamichi Nobushima Keisuke Murakami Mari Kitade Ryohei Kuwatsuru |
| author_facet | Yoshimi Nozaki Shiori Takeuchi Masafumi Arai Yoshiki Kuwatsuru Hiroshi Toei Shingo Okada Hitomi Kato Naoko Saito Takamichi Nobushima Keisuke Murakami Mari Kitade Ryohei Kuwatsuru |
| author_sort | Yoshimi Nozaki |
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| description | Abstract Background Classifying uterine fibroid using the International Federation of Gynecology and Obstetrics (FIGO) classification system assists treatment decision-making and planning. This study aimed to study whether different fibroid locations influence clinical outcomes following uterine artery embolization (UAE). Methods This is a retrospective cohort study of patients who underwent UAE for symptomatic uterine fibroid between December 2016 and January 2023 at our hospital. Changes in mean fibroid volume were compared based on MR images. Menstrual pain, excessive flow symptoms, and treatment satisfaction before UAE and 6 months after UAE were compared. Results A total of 149 premenopausal patients (mean age 45.7 ± 2.7 years) were included for analysis (FIGO 2/3, n = 57; FIGO 4–7, n = 92). Baseline menstrual pain, fibroid, and uterine volume before UAE were comparable between the two FIGO groups (p > 0.05). The menstrual flow index was higher for the FIGO 2/3 group (mean ± SD [min–max]: 9.4 ± 1.4 [4–10] vs 8.0 ± 2.3 [0–10], p < 0.001). Six months after UAE, the improvements in menstrual flow index (mean ± SD]: -3.7 ± 2.6 vs -2.6 ± 2.2, p = 0.035), fibroid volume (mean ± SD: -54.7 ± 21.7% vs -39.8 ± 16.2%, p < 0.001), and uterine volume (mean ± SD: -38.2 ± 16.3% vs -31.1 ± 11.6%, p = 0.008) in the FIGO 2/3 group were significantly higher than the FIGO 4–7 group. Both groups had comparable improvements in menstrual pain index (-2.1 ± 2.6 vs -1.8 ± 2.5, p = 0.008) and 88% of the patients were satisfied or very satisfied overall. Conclusion UAE treatment satisfaction was high for patients with fibroids at different FIGO stages. UAE treatment outcomes were better for patients with fibroids affecting the endometrium (FIGO 2/3). Level of evidence 3B, Retrospective observational study. |
| format | Article |
| id | doaj-art-4a88d4ed607b480a91c30a4ddf4202b0 |
| institution | Kabale University |
| issn | 2520-8934 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SpringerOpen |
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| series | CVIR Endovascular |
| spelling | doaj-art-4a88d4ed607b480a91c30a4ddf4202b02025-02-02T12:44:18ZengSpringerOpenCVIR Endovascular2520-89342025-01-01811810.1186/s42155-025-00520-7Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classificationYoshimi Nozaki0Shiori Takeuchi1Masafumi Arai2Yoshiki Kuwatsuru3Hiroshi Toei4Shingo Okada5Hitomi Kato6Naoko Saito7Takamichi Nobushima8Keisuke Murakami9Mari Kitade10Ryohei Kuwatsuru11Department of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Juntendo UniversityDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Juntendo UniversityDepartment of Radiology, Graduate School of Medicine, Juntendo UniversityAbstract Background Classifying uterine fibroid using the International Federation of Gynecology and Obstetrics (FIGO) classification system assists treatment decision-making and planning. This study aimed to study whether different fibroid locations influence clinical outcomes following uterine artery embolization (UAE). Methods This is a retrospective cohort study of patients who underwent UAE for symptomatic uterine fibroid between December 2016 and January 2023 at our hospital. Changes in mean fibroid volume were compared based on MR images. Menstrual pain, excessive flow symptoms, and treatment satisfaction before UAE and 6 months after UAE were compared. Results A total of 149 premenopausal patients (mean age 45.7 ± 2.7 years) were included for analysis (FIGO 2/3, n = 57; FIGO 4–7, n = 92). Baseline menstrual pain, fibroid, and uterine volume before UAE were comparable between the two FIGO groups (p > 0.05). The menstrual flow index was higher for the FIGO 2/3 group (mean ± SD [min–max]: 9.4 ± 1.4 [4–10] vs 8.0 ± 2.3 [0–10], p < 0.001). Six months after UAE, the improvements in menstrual flow index (mean ± SD]: -3.7 ± 2.6 vs -2.6 ± 2.2, p = 0.035), fibroid volume (mean ± SD: -54.7 ± 21.7% vs -39.8 ± 16.2%, p < 0.001), and uterine volume (mean ± SD: -38.2 ± 16.3% vs -31.1 ± 11.6%, p = 0.008) in the FIGO 2/3 group were significantly higher than the FIGO 4–7 group. Both groups had comparable improvements in menstrual pain index (-2.1 ± 2.6 vs -1.8 ± 2.5, p = 0.008) and 88% of the patients were satisfied or very satisfied overall. Conclusion UAE treatment satisfaction was high for patients with fibroids at different FIGO stages. UAE treatment outcomes were better for patients with fibroids affecting the endometrium (FIGO 2/3). Level of evidence 3B, Retrospective observational study.https://doi.org/10.1186/s42155-025-00520-7FibroidMenstrual complicationsFIGO stagingUterine artery embolizationTreatment response |
| spellingShingle | Yoshimi Nozaki Shiori Takeuchi Masafumi Arai Yoshiki Kuwatsuru Hiroshi Toei Shingo Okada Hitomi Kato Naoko Saito Takamichi Nobushima Keisuke Murakami Mari Kitade Ryohei Kuwatsuru Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification CVIR Endovascular Fibroid Menstrual complications FIGO staging Uterine artery embolization Treatment response |
| title | Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification |
| title_full | Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification |
| title_fullStr | Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification |
| title_full_unstemmed | Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification |
| title_short | Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification |
| title_sort | postoperative symptom changes following uterine artery embolization for uterine fibroid based on figo classification |
| topic | Fibroid Menstrual complications FIGO staging Uterine artery embolization Treatment response |
| url | https://doi.org/10.1186/s42155-025-00520-7 |
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