MMP-2—Potential Predictor of Epithelial–Mesenchymal Transition in Squamous Cell Carcinogenesis

MMP-2—Potential Predictor of Epithelial–Mesenchymal Transition in Squamous Cell Carcinogenesis

Epithelial–mesenchymal transition (EMT) is one of the key steps in cutaneous carcinogenesis. At the molecular level, this cellular dedifferentiation is modulated by the interaction of signalling pathways that favour basement membrane degradation under the influence of proinflammatory cytokines and m...

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Bibliographic Details
Main Authors: Doinița Temelie-Olinici, Bild Walther, Laura Gheucă-Solovăstru, Mihaela Perțea, Daniela-Anicuța Leca, Bogdan-Vasile Grecu, Ioana-Alina Halip, Mădălina Mocanu, Ioana-Adriana Popescu, Adriana-Ionela Pătrașcu, Dan Vâță
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Life
Subjects:
MMP-2
carcinogenesis
epithelial–mesenchymal transition
premalignant skin lesions
Online Access:https://www.mdpi.com/2075-1729/15/7/1060
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